ID A0A2Y9P9H1_DELLE Unreviewed; 423 AA.
AC A0A2Y9P9H1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2021, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=UDP-N-acetylglucosamine transporter {ECO:0000256|ARBA:ARBA00040900};
DE AltName: Full=Golgi UDP-GlcNAc transporter {ECO:0000256|ARBA:ARBA00041527};
DE AltName: Full=Solute carrier family 35 member A3 {ECO:0000256|ARBA:ARBA00041936};
GN Name=SLC35A3 {ECO:0000313|RefSeq:XP_022439953.2};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022439953.2};
RN [1] {ECO:0000313|RefSeq:XP_022439953.2}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022439953.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35A
CC subfamily. {ECO:0000256|ARBA:ARBA00009976}.
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DR RefSeq; XP_022439953.2; XM_022584245.2.
DR STRING; 9749.A0A2Y9P9H1; -.
DR KEGG; dle:111180122; -.
DR InParanoid; A0A2Y9P9H1; -.
DR OrthoDB; 200085at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR NCBIfam; TIGR00803; nst; 1.
DR PANTHER; PTHR10231; NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR10231:SF36; UDP-N-ACETYLGLUCOSAMINE TRANSPORTER; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022597}.
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 46120 MW; 35E3E19C1A01328E CRC64;
MEPTSADLRP PERSRERYSP GPRRKPEHLG DWTAGTRKRL GRTGPAAATA AGAGAAALXG
VAGTRRAPQP GGPGGAEPPP PVRAAGRAAW EANEDKTMSA NLKYLSLGIL VFQTTSLVLT
MRYSRTLKEE GPRYLSSTAV VVAELWKIMA CILLVYKDSK CSLRALNRIL HDEILNKPME
TLKLAIPSGI YTLQNNLLYV ALSNLDAATY QVTYQLKILT TALFSVSMLS KKLGVYQWLS
LVILMTGVAF VQWPSDSQEL NSKELSAGSQ FVGLMAVLTA CFSSGFAGVY FEKILKETKQ
SVWIRNIQLG FFGSIFGLMG VYVYDGELVS KNGFFQGYNW LTWIVVVLQA LGGLVIAAVI
KYADNILKGF ATSLSIILST LISYFWLQDF VPTSVFFLGA ILVITATFLY GYDPKPAGNP
TKA
//
