ID A0A2Y9P9Y3_DELLE Unreviewed; 1201 AA.
AC A0A2Y9P9Y3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=AP-4 complex subunit epsilon-1 isoform X1 {ECO:0000313|RefSeq:XP_022442820.1};
GN Name=AP4E1 {ECO:0000313|RefSeq:XP_022442820.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022442820.1};
RN [1] {ECO:0000313|RefSeq:XP_022442820.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022442820.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022442820.1; XM_022587112.2.
DR AlphaFoldDB; A0A2Y9P9Y3; -.
DR STRING; 9749.A0A2Y9P9Y3; -.
DR KEGG; dle:111181596; -.
DR InParanoid; A0A2Y9P9Y3; -.
DR OrthoDB; 25313at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0030124; C:AP-4 adaptor complex; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR017109; AP4_complex_esu.
DR InterPro; IPR028269; AP4E1_C.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR22780; ADAPTIN, ALPHA/GAMMA/EPSILON; 1.
DR PANTHER; PTHR22780:SF13; AP-4 COMPLEX SUBUNIT EPSILON-1; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF14807; AP4E_app_platf; 1.
DR PIRSF; PIRSF037097; AP4_complex_epsilon; 1.
DR SMART; SM01356; AP4E_app_platf; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1033..1136
FT /note="AP-4 complex subunit epsilon-1 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01356"
SQ SEQUENCE 1201 AA; 134880 MW; 54CB949BCC263504 CRC64;
MSDIVEKTLT ALPGLFLQNQ SASGPAAAKA SFSSRLGGLV RGITALTSKH EEEKLIQQEL
SNLKATVSAP TTTLKMMKEC MVRLIYCEML GYDASFGYIH AIKLAQQGNL LEKRVGYLAV
SLFLHESHEL LLLLVNTVVK DLQSTNLVEV CMALTIVSQI FPREMIPAVL PLIEDKLQHS
KEIIRRKAVL ALYKFYLIAP NQVQHIHIKF RKALCDRDVG VMAASLHIYL RMIKENSSAY
KDLTGSFVTI LKQVVGGKLP IDFNYHSVPA PWLQIQLLRI LGLLGKDDQR TSELMYDVLD
ESLRRAELNH NVTYAILFEC VHTVYSIYPK SELLEKAAKC IGKFVLSPKI NLKYLGLKAL
TYVIQQDPTL ALQHQMTIIE CLDHPDPIIK RETLELLYRI TNAQNITVIV QKMLEYLHQS
KEEYIIVNLV GKIAELAEKY APDNAWFVQT MNAVFSVGGD VMHPDIPNNF LRVLAEGFDD
ETENQQLRLY AVQSYFTLLD VENVFYPQRF LQVMSWVLGE YSYLLDKETP EEVITKLYKL
LRSDSISSET KAWIIAAVTK LTPQAHSSNI VERLIQEFTT SLDTCLRQHA FELKHLHENV
KFMKGLLPVD KSCEDMVVDA SLSFLDGFVA EELSQGAAPY KPHHQRQEEK LSQEKVLSFE
PYGLSFSSSG FSGRQSPAGI SLGSDISGNS TETGLKETNS LKLEGIKKLW GKEGYLPKKE
SKTGDETEAL PVPQENIIME NVDQIITKND QSQALTQSKE EKEKQLLASS LFVGLGSEST
INLLGKADTL SHKFRRKSKV KETKSGQTTT AQNMTCSSFS SSSNVTYEED YYLDHLQDRG
DKEVKKFSLN SELLDSESLT ELPLVEKISN CRLSTPSLFA DNNMEVFHPP QSTAASVANE
ISLAASLLEE TTEHMHSDLM EVCNNETISV SSYKIWKDEC LLMVWSVFNK SASELKSANL
EIAPAENFKI TEQPGCCLPV IEAESTKNFQ YSVQMEKPFT EGNLSGFINY QVMDTHSVQL
EFSVNLSLLD FIRPLKISTE DFGKLWLSFA NDVKQNVKMS ESQAALPSTL KALQQELRLH
VVDIIGNEGL LACQLLPSIP CLLHFRVHGD MLALWFRSSC STLPDYLLYQ CQKVRAWIDP
QVPVPIPCFH PGLTRAFKAE CFVSVFLSSR CKKHGKSGGD LVSKDSESPG HLCIVYPKTQ
S
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