ID A0A2Y9PA56_DELLE Unreviewed; 379 AA.
AC A0A2Y9PA56;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Neutrophil cytosol factor 1 isoform X7 {ECO:0000313|RefSeq:XP_022443834.1};
GN Name=NCF1 {ECO:0000313|RefSeq:XP_022443834.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022443834.1};
RN [1] {ECO:0000313|RefSeq:XP_022443834.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022443834.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022443834.1; XM_022588126.2.
DR AlphaFoldDB; A0A2Y9PA56; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IEA:InterPro.
DR CDD; cd12021; SH3_p47phox_1; 1.
DR CDD; cd12022; SH3_p47phox_2; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR032136; NCF1_PBR/AIR.
DR InterPro; IPR035756; NCF1_SH3_1.
DR InterPro; IPR035757; NCF1_SH3_2.
DR InterPro; IPR001655; P47PHOX.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15706:SF6; NEUTROPHIL CYTOSOL FACTOR 1-RELATED; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF16621; NCF1_PBR_AIR; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00018; SH3_1; 2.
DR PRINTS; PR00498; P47PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00312; PX; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..99
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 143..202
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 213..272
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 272..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..301
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 379 AA; 43505 MW; D958771DA58A15AB CRC64;
MFLVKWQDLS EKVVYRRFTE IYEFHKILKE MFPIEAGDIN PENRIIPHLP APRWFDGQRV
AESRQGTLTE YCNSLMNLPG KISRCPHLLN FFKVRPDDLK LPTDSHGPHF PRSFWELSWV
KKPETYLMPR DGKSNAADIT GPIILQTYRA IADYEKSSGS EMALATGDVV DVVEKSQSGW
WFCQMKTKRG WVPASYLEPL DSPDEAEDPE PNYAGEPYIT IKAYTALLED EISLEQGETI
EVIHKLLDGW WVIRKEDVTG YFPSMYLQQA GQDTDQAQSR IKRGAPPRRS SIRNAHSIHQ
RSRKRLSQDT YRRNSVRFLQ QRPRGARPGP RSPGSALRFA GPRLSCSEPT CARVQQKLAP
PDFRCEPVHP SFTSQEVSL
//
