ID A0A2Y9PAZ0_DELLE Unreviewed; 1063 AA.
AC A0A2Y9PAZ0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Protein Jumonji isoform X6 {ECO:0000313|RefSeq:XP_022442421.1};
GN Name=JARID2 {ECO:0000313|RefSeq:XP_022442421.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022442421.1};
RN [1] {ECO:0000313|RefSeq:XP_022442421.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022442421.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022442421.1; XM_022586713.2.
DR AlphaFoldDB; A0A2Y9PAZ0; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd16870; ARID_JARD2; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR003349; JmjN.
DR InterPro; IPR004198; Znf_C5HC2.
DR PANTHER; PTHR10694; LYSINE-SPECIFIC DEMETHYLASE; 1.
DR PANTHER; PTHR10694:SF113; PROTEIN JUMONJI; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF02375; JmjN; 1.
DR Pfam; PF02928; zf-C5HC2; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00545; JmjN; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS51183; JMJN; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 382..423
FT /note="JmjN"
FT /evidence="ECO:0000259|PROSITE:PS51183"
FT DOMAIN 446..538
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT DOMAIN 708..872
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 1..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1063
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..22
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..92
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1063 AA; 118324 MW; B5AF22D9B2FEEECE CRC64;
MVYFGSSQDE EDIEEEDDET EDVKTATNNA SSSCQSTPRK GKAHKHVHNG HVFNGSSRSS
REKEPVQKHK SKEATPAKEK HSDPRADGRR EQASTSHPPA APSAGSSARG LPAYHHPPLH
RSAQDLRKQV SKVGGVTRMS SLGTSAASAK KMREVRPSPS KTVKYTATVT KGTVTYTKAK
RELVKETKPN HHKPSSAVNH TISGKTESSN AKTRKQVLSL GGASKSTGHT VNGLKVSGRL
NPKSCTKEGG GRQLREGLRN SKRRLEEAPP GDKPQSPPKK MKGEAGAAEG PGRKAAPAPA
EKAPPGGHGK KEVPERSLER NRPKRVSAGK GPPGRQAHGK PDGAPCENRS TSQSEPLPRP
HEAAAKAEKG AGRAGWAAMD EIPVLRPSAK EFHDPLVYIE SVRPQVEKYG MCRVIPPPDW
RPECKLNDEM RFVTQIQHIH KLGRRWGPNV QRLACIKKHL RSQGITMDEL PLIGGCELDL
ACFFRLINEM GGMQQVTDLK KWNKLADMLR IPKTAQDRLA KLQEAYCQYL LSYDSLSPEE
HRRLEKEVLM EKESLERRKG PLEGHTEQDY NRFHPLPRFE PKNGLINGVA HRNGFRSKLK
EVGPAQLKTG RRRLFAQEKE VVKEEDDRGI LSDFHKCIYK GRSVSLTTFY RTARNIMNMC
FSKEPAPAEI EQEYWRLVEE KDCHVAVHCG KVDTNTHGSG FPVGKSEPFS RHGWNLTVLP
NNTGSILRHL GAVPGVTIPW LNIGMVFSTS CWSRDQNHLP YIDYLHTGAD CIWYCIPAEE
ENKLEDVVHT LLQANGTPGL QMLESNVMIS PEVLCREGIK VHRTVQQSGQ FVVCFPGSFV
SKVCCGYSVS ETVHFATTQW TSMGFETAKE MKRRHIAKPF SMEKLLYQIA QAEAKKENGP
TLSTISALLD ELRDTELRQR RQLFEAGLHS SARYGSHEGS SAAPDGKKKP RKWLQLETSE
RRCQICQHLC YLSMVVQENE NVVFCLECAL RHVEKQKSCR GLKLMYRYDE EQIISLVNQI
CGKVSGKNGS IENCLGKPTP KRGPRKRATV DVPPSRLAAA SSS
//
