ID   A0A2Y9PCW4_DELLE        Unreviewed;       958 AA.
AC   A0A2Y9PCW4;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=General transcription factor II-I repeat domain-containing protein 1 isoform X3 {ECO:0000313|RefSeq:XP_022443810.1};
GN   Name=GTF2IRD1 {ECO:0000313|RefSeq:XP_022443810.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022443810.1};
RN   [1] {ECO:0000313|RefSeq:XP_022443810.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022443810.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_022443810.1; XM_022588102.2.
DR   AlphaFoldDB; A0A2Y9PCW4; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 3.90.1460.10; GTF2I-like; 5.
DR   InterPro; IPR004212; GTF2I.
DR   InterPro; IPR036647; GTF2I-like_rpt_sf.
DR   InterPro; IPR016659; TF_II-I.
DR   PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46304:SF1; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02946; GTF2I; 5.
DR   PIRSF; PIRSF016441; TF_II-I; 2.
DR   SUPFAM; SSF117773; GTF2I-like repeat; 5.
DR   PROSITE; PS51139; GTF2I; 5.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          115..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          251..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          300..336
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          488..512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          530..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          897..928
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        115..129
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        561..577
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        913..928
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   958 AA;  106202 MW;  EB0D984ABD7913E6 CRC64;
     MPRPMAHGHL RLFPSSIQAT MALLGKRCDV PTNGCGPDRW NSAIARKDEI ITSLVSALDS
     MCSALSKLNA EVACVAVHDE SAFVVGTEKG RMFLNARKEL QSDFLRFCRG PPWKEPEAEH
     PKKVPRGEGG SRNIPRSALE HGSDVYLLRK MVEEVFDVLY SEALGRASVV PLPYERLLRE
     PGLLAVQGLP EGLAFRRPAE YDPKALMAIL EHSHRIRFKL KRPLEDGGRD SKALVELNGI
     SLIAKGSRDC GLHGQAPKGP PQDLPPTATS SSVASFLYST ALANRTAREL KQEAPACPLA
     SSDLGLGRPG PEPKAPTAQD FPDCCGQKPT GPGGPLIQNV HASKRILFSI VHDKSEKWDA
     FIKETEDINT LRECVQILFN SRYAEALGLD HMVPVPYRKI ACDPEAVEIV GIPDKIPFKR
     PCTYGVPKLK RILEERHSIH FVIKRMFDER IFTGNKFTKD PTKLEPASPP EDISAEVSRA
     AVLDLAGTAR SDKSSLSEDC GPGTSGELGG LRPIKIEPED LDIIQVTVPD PSPTSEEMTD
     SMPGHVPSED SGYGMEMLTD KGPSEDPRPE ERPVEDSHGD VIRPLRKQVE LLFNTRYAKA
     IGISEPVKVP YSKFLMYPEE LFVVGLPEGI SLRRPNCFGI AKLRKILEAS NSIQFVIKRP
     ELLTEGVKEP LTDSQERDSG DPLVDESLKR QGFQENYDAR LSRIDIANTL REQVQDLFNK
     KYGEALGIKY PVQVPYKRIK SNPGSVIIEG LPPGIPFRKP CTFGSQNLER ILAVADKIKF
     TVTRPFQGLI PKPDEDDANR LGEKVILREQ VKELFNEKYG EALGLNRPVL VPYKLIRDSP
     DAVEVTGLPD DIPFRNPNTY DIHRLEKILK AREHVRMVII NQLQPFAEIC NDAKVPAKDS
     SIPKRKRKRV SEGNSISSSS SSNPESVAST NQISLVQWPM YMVDYTGLNV QLPGPLNY
//