ID   A0A2Y9PE47_DELLE        Unreviewed;       961 AA.
AC   A0A2Y9PE47;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Ras-interacting protein 1 {ECO:0000313|RefSeq:XP_022440858.1};
GN   Name=RASIP1 {ECO:0000313|RefSeq:XP_022440858.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022440858.1};
RN   [1] {ECO:0000313|RefSeq:XP_022440858.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022440858.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_022440858.1; XM_022585150.2.
DR   AlphaFoldDB; A0A2Y9PE47; -.
DR   STRING; 9749.A0A2Y9PE47; -.
DR   Ensembl; ENSDLET00000001199; ENSDLEP00000001032; ENSDLEG00000000906.
DR   KEGG; dle:111180650; -.
DR   InParanoid; A0A2Y9PE47; -.
DR   OrthoDB; 2949378at2759; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
DR   GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR   GO; GO:0051020; F:GTPase binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0010507; P:negative regulation of autophagy; IEA:Ensembl.
DR   GO; GO:1905709; P:negative regulation of membrane permeability; IEA:Ensembl.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0033625; P:positive regulation of integrin activation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   CDD; cd22734; FHA_RAIN; 1.
DR   CDD; cd15472; Myo5p-like_CBD_Rasip1; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   InterPro; IPR037983; CBD_Rasip1/Radil.
DR   InterPro; IPR002710; Dilute_dom.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR16027; DILUTE DOMAIN-CONTAINING PROTEIN YPR089W; 1.
DR   PANTHER; PTHR16027:SF4; RAS-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF01843; DIL; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM01132; DIL; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS51126; DILUTE; 1.
DR   PROSITE; PS50200; RA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT   DOMAIN          142..257
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          598..895
FT                   /note="Dilute"
FT                   /evidence="ECO:0000259|PROSITE:PS51126"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          35..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          265..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   961 AA;  103218 MW;  33C157CB173C1119 CRC64;
     MLSGERKEGG SPRFGKLHLP VGLWINSPRK QLAKLGRRWP SAVSVKSSSS DTGSRSSEPL
     PPPPPHVELR RVGAVKAAGG ASGSRAKRIS QLFRGSGTTG SGGAGAPGTP GAAQRWASEK
     KLPELAAGVA PEPPLAARAT APPGVLKIFG AGLASGANYK SVLATARSTA RELVAEALER
     YGLAGSPGSG PGESSCVDAF ALCDALGRPA AGAIGSCEWR AEHLRVLGDS ERPLLVQELW
     RARPGWARRF ELRGREEARR LEQEAFGAAD GDGTGAPSWR PQKNRSRAAS GGAALASPGP
     GSGSGPSAGS GGKERSENLS LRRSVSELSL QGRRRRQQER RQQALSMAPG AADAQIGPVD
     PGDFDQLTQC LIQAPSNRPY FLLLQGYQDA QDFVVYVMTR EQHVFGRGGN SSARGGSPAP
     YVDTFLNAPD ILPRHCTVRA GPEPPAMVRP SRGAPVTHNG CLLLRETELH PGDLLGLGEH
     FLFMYKDPRA GGAGPARPPW LPARPGATPP GPGWAFSCRL CGRGLQERGE ALAAYLDGRE
     PVLRFRPREE EALLGEIVRA AAAGAGDLPP LGPATLLALC VQHSARELEL GHLPRLLGRL
     ARLIKEAVWE KIKEIGDRQP ENHPEGVPEV PLTPEAVSVE LRPLMLWMAN TTELLSFVQE
     KVLEMEKEAD QEDPQLCNDL ELCDEAMALL DEVIMCTFQQ SVYYLTKTLY STLPALLDSN
     PFTAGAELPG PGAELGAMPP GLRPTLGVFQ AALELTSQCE LHPDLVSQTF GYLFFFSNAS
     LLNSLMERGQ GRPFYQWSRA VQIRTNLDLV LDWLQGAGLG DIATEFFRKL SIAVNLLCVP
     RTSLLKASWS SLRTDHPTLT PAQLHHLLSH YQLGPGRGPP PAWDPPPAER DAVDTGDIFE
     SFSSHPPLIL PLGSSRLSLT GPVTDDALHR ELRRLRRLLW DLEQQELPAN HRHGPPVATP
     P
//