ID   A0A2Y9PIH2_DELLE        Unreviewed;       601 AA.
AC   A0A2Y9PIH2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=SH2 domain-containing protein 4B {ECO:0000313|RefSeq:XP_022446729.1};
GN   Name=SH2D4B {ECO:0000313|RefSeq:XP_022446729.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022446729.1};
RN   [1] {ECO:0000313|RefSeq:XP_022446729.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022446729.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_022446729.1; XM_022591021.2.
DR   AlphaFoldDB; A0A2Y9PIH2; -.
DR   STRING; 9749.A0A2Y9PIH2; -.
DR   KEGG; dle:111183571; -.
DR   InParanoid; A0A2Y9PIH2; -.
DR   OrthoDB; 5361172at2759; -.
DR   Proteomes; UP000248483; Unplaced.
DR   CDD; cd10351; SH2_SH2D4B; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR035839; SH2D4B_SH2.
DR   PANTHER; PTHR14388:SF7; SH2 DOMAIN-CONTAINING PROTEIN 4B; 1.
DR   PANTHER; PTHR14388; T CELL-SPECIFIC ADAPTER PROTEIN TSAD; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN          495..587
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          136..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          366..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          322..356
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        370..401
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   601 AA;  69346 MW;  A5E323EDCD407604 CRC64;
     MELIGKAASS SSSYLWRRDR FPVGWGSVID IAGVIVTFHE QITRHLPGPG RAGPGFCPQS
     WRLSLSHCPR AQGRPRHRLC WDVALGDPVE GLDSSWCWIP LAGPGCLFAS CCLIPVAVLG
     RGDEFVAGWE LRQSDDAAQR SGSGSDRGVR SQGRGVAWGV PPGVCIPGDT MLQQILHDMY
     IDPELLAELS DVQKHILFYK MREEQLRRWR EREAWEALAQ FEGLRPPKVK RASDKHIQWL
     LGADGEVWVW VMGEGPGDKP YEEISEELIA ERARLQAQRE AEELWRQKEA EITKKFRDAL
     ANEKARILVE KWKVETEDRK AAKILEERIH EEFKRKEEEE RKRGEEQIRL QEEQRAKELY
     WTLKQAQLQS HPSEKEEREW EEQLRRSKAA DEERRRRAQR ARDEYRRHSL RAIQKGTVAG
     LSSRFRELGQ SHEQEARLYH HLLGPGLPSP LAVPGRTWER PLCPVSREVI VRWFKEEQLP
     RRAGFERSTK AIAPWFHGII SREDAEDLLE NMTEGAFLVR VSEKIWGYTL SYRLQKGFKH
     FLVDASGDFY SFLGVDPNRH ATLTDLIDFH KEEIITVSGG ELLQEPCGQR DSPPDYHLLF
     E
//