ID A0A2Y9PJ75_DELLE Unreviewed; 262 AA.
AC A0A2Y9PJ75;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Homeobox protein CDX-1 isoform X1 {ECO:0000313|RefSeq:XP_022445825.1};
GN Name=CDX1 {ECO:0000313|RefSeq:XP_022445825.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022445825.1};
RN [1] {ECO:0000313|RefSeq:XP_022445825.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022445825.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR RefSeq; XP_022445825.1; XM_022590117.2.
DR AlphaFoldDB; A0A2Y9PJ75; -.
DR STRING; 9749.A0A2Y9PJ75; -.
DR KEGG; dle:111183089; -.
DR InParanoid; A0A2Y9PJ75; -.
DR OrthoDB; 728401at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR006820; Caudal_activation_dom.
DR InterPro; IPR047152; Caudal_homeobox.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24332; HOMEOBOX PROTEIN CDX; 1.
DR PANTHER; PTHR24332:SF16; HOMEOBOX PROTEIN CDX-1; 1.
DR Pfam; PF04731; Caudal_act; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 148..194
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 150..195
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 11..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..108
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 262 AA; 27855 MW; E41A05AE99118540 CRC64;
MYVGYVLDKE SPVYPGPARP ASLGLGPQAY GPPPPPQYPD FTGYSHVEPG PVPPAAWSTP
FSAPKDEWAA AYSPGPAAST ASPAPLAFGP PPDFSAVPAP PGPGPGLLAQ PLSGPGAPSS
PGAQRRTPYE WMRRSVAAGG GGGSGKTRTK DKYRVVYTDH QRLELEKEFH YSRYITIRRK
SELAANLGLT ERQVCGAPTS ATGAVPGVWP PGCQADYGAQ SREENREVVS QPWSYNTIET
ELLPIPRPIK PNIPDHQEEH GA
//
