ID   A0A2Y9PPU5_DELLE        Unreviewed;       324 AA.
AC   A0A2Y9PPU5;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Zinc transporter ZIP13 {ECO:0000256|ARBA:ARBA00040592};
DE   AltName: Full=Solute carrier family 39 member 13 {ECO:0000256|ARBA:ARBA00042542};
DE   AltName: Full=Zrt- and Irt-like protein 13 {ECO:0000256|ARBA:ARBA00042972};
GN   Name=SLC39A13 {ECO:0000313|RefSeq:XP_022447730.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022447730.1};
RN   [1] {ECO:0000313|RefSeq:XP_022447730.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022447730.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351,
CC         ChEBI:CHEBI:29105; Evidence={ECO:0000256|ARBA:ARBA00034634};
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC       {ECO:0000256|ARBA:ARBA00004156}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC       {ECO:0000256|ARBA:ARBA00006939}.
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DR   RefSeq; XP_022447730.1; XM_022592022.2.
DR   AlphaFoldDB; A0A2Y9PPU5; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003689; ZIP.
DR   PANTHER; PTHR16950; ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4; 1.
DR   PANTHER; PTHR16950:SF16; ZINC TRANSPORTER ZIP13; 1.
DR   Pfam; PF02535; Zip; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..324
FT                   /note="Zinc transporter ZIP13"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015964404"
FT   TRANSMEM        68..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        109..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   324 AA;  33925 MW;  C667276325B470F0 CRC64;
     MPGCPCPGCG MAGQRLLFLA ALALELLGGA GGSQQAFRSR GVAAACRLDN KESESWGALL
     SGERLDTWIC SLLGSLMVGL SGVFPLLVIP LEMGTTLRSE AGARRLKQLL SFALGGLLGN
     VFLHLLPEAW AYTYSASPGG EGQSLQQQQQ LGLWVIAGFL TFLALEKMFL DSKEEETSQA
     PSKDPAAAAA LSGGHHLAQP AAGPGLSAVV RNIKVSGYLN LLANTIDNFT HGLAVAASFL
     VSKKIGLLTT MAILLHEIPH EVGDFAILLR AGFDRWSAAK LQLSTALGGL LGACFAICTQ
     SPKGRRLWPG SCPSPLAAFS TSPW
//