ID A0A2Y9PQC1_DELLE Unreviewed; 679 AA.
AC A0A2Y9PQC1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Regulator of G-protein signaling 9 isoform X3 {ECO:0000313|RefSeq:XP_022445522.1};
GN Name=RGS9 {ECO:0000313|RefSeq:XP_022445522.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022445522.1};
RN [1] {ECO:0000313|RefSeq:XP_022445522.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022445522.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
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DR RefSeq; XP_022445522.1; XM_022589814.2.
DR AlphaFoldDB; A0A2Y9PQC1; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR CDD; cd08739; RGS_RGS9; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR047077; RGS9_RGS.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF1; REGULATOR OF G-PROTEIN SIGNALING 9; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 310..425
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 467..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..513
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 679 AA; 77705 MW; F02AF02B1D926B43 CRC64;
MTIRHQGQQY RPRMAFLRKI EALVKDMQDP EMGVRVQNQK VTVISVPHAM TEAQNLGNFI
VKYGYIYPLQ DPKNLVLKPD NSLYRFQTPY FWPTQQWPAE DTDYAIYLAK RNIKKKGILE
EYEKENYNFL NKKINYKWDF VIMQAKEQYR AEKERNKADR YALDRQEKAY WLVHRCPGGK
RPLYPVWRLR AVGRPCACIP CQPGMNDVLD YGLDRVTDPS EVQVKQKQTV VSVRKEIMYY
RQALMRSTVK SSVSLGGIVK YSEQFSSNDA IMSGCLPSNP WVTDDTQFWD LNAKLVEFPT
KMRVERWAFN FSELIRDPKG RQSFQYFLKK EFSGENLGFW EACEDLKYGD QSKVKEKAEE
IYKLFLAPGA RRWINIDGKT MDITVKGLKH PHRYVLDAAQ THIYMLMKKD SYARYLKSPV
YKEMLARAVE PQETTKRSSS LRFMRRPLRS SPSPVILRQL EEEAKAREAA NTVDITQPDQ
RAAPSPHLTV YTGAPLPSSP SSPRSPRCRS PRRPFPSPGR FLRRPSSTVC PSPIKVALEG
SPGEEPEREA ARGRSGAETS GASADQPRPR ALPKARVALS LGRFLRRGCL ASPVFARLSP
RCPPVPHGKV QPLGEAGRQL PRPRSRRAAN FFQMKMDVST GSGTCLVDSE DTRTGERSDQ
AIEKEVICPW ESLAEGKAS
//
