ID A0A2Y9PV49_DELLE Unreviewed; 686 AA.
AC A0A2Y9PV49;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=TRMT1-like protein {ECO:0000256|ARBA:ARBA00015939};
GN Name=TRMT1L {ECO:0000313|RefSeq:XP_022449076.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022449076.1};
RN [1] {ECO:0000313|RefSeq:XP_022449076.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022449076.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May play a role in motor coordination and exploratory
CC behavior. {ECO:0000256|ARBA:ARBA00003652}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Trm1 family. {ECO:0000256|PROSITE-ProRule:PRU00958}.
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DR RefSeq; XP_022449076.1; XM_022593368.2.
DR AlphaFoldDB; A0A2Y9PV49; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007610; P:behavior; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002905; Trm1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR10631; N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10631:SF1; TRMT1-LIKE PROTEIN; 1.
DR Pfam; PF02005; TRM; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51626; SAM_MT_TRM1; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 3: Inferred from homology;
KW Behavior {ECO:0000256|ARBA:ARBA00022610};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00958};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00958};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; tRNA processing {ECO:0000256|PROSITE-ProRule:PRU00958};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 233..260
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..59
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 76170 MW; C5C3ACF551BDFF34 CRC64;
MENMAEEELL PQEKEEEEEV EVAQVQVPTP APDSARVPAP APDSAPASAP TPASAPVPAP
ALAQAPTLSP SLASAPDEAE SNGLVSPLKS VLTGQNEDGI SEIELKIEEK EVLKEPPSIL
DSSDLTRERH ISIQRQLADL EKLAFVTEGD FDSASSLNSD NLDAGNKQAC PLCPKEKFRA
CNSHKLHRHL QNLHWKVSVE FEGYRMCICH LPCRPVKPNI IGEQISSKMG AHYHCIICSA
TITRRTDMLG HVRRHVNKGE TKSTYIAASA AKPPNEILKE ADTDVQVCPN YSVPQKTDSY
FNPKMKLNRQ LIFCTLAALA KERKPLECLD AFGATGIMGL QWAKHLGNAV KVTINDLNEN
SVTLIQENCH LNKLKVVVDS KEKEESDDIP EEGEENFGNI KVTKMDANVL MHLRSFDFIH
LDPFGTSVNY LDSAFRNIRN LGIVSVTSTD ISSLYAKAQH VARRHYGCNI VRTEYYKELA
ARIVVAAVAR AAARCNKGIE VLFAVALEHF VLVVVRVLRG PTSADETAKK IQYLIHCQWC
EERIFQKDGN MVEENPYRQL PCNCHGSMPG KTAIELGPLW SSSLFNTGFL KRMLFESLHY
GLDDIQTLIK TLIFESECTP QSQFSVHAPS NLNKQEEYGV FIKTTDDTTT DNYIAQGIPL
INQKTLYSGH KNLLRGLSYN LGKEKK
//
