ID A0A2Y9Q1N5_DELLE Unreviewed; 525 AA.
AC A0A2Y9Q1N5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Ankyrin repeat and SOCS box protein 3 {ECO:0000313|RefSeq:XP_022453009.1, ECO:0000313|RefSeq:XP_022453010.1};
GN Name=ASB3 {ECO:0000313|RefSeq:XP_022453009.1,
GN ECO:0000313|RefSeq:XP_022453010.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022453009.1};
RN [1] {ECO:0000313|RefSeq:XP_022453009.1, ECO:0000313|RefSeq:XP_022453010.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022453009.1,
RC ECO:0000313|RefSeq:XP_022453010.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_022453009.1; XM_022597301.1.
DR RefSeq; XP_022453010.1; XM_022597302.1.
DR STRING; 9749.A0A2Y9Q1N5; -.
DR Ensembl; ENSDLET00000029741; ENSDLEP00000027056; ENSDLEG00000019544.
DR KEGG; dle:111186571; -.
DR OrthoDB; 662654at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03722; SOCS_ASB3; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037329; ASB3_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24173; ANKYRIN REPEAT CONTAINING; 1.
DR PANTHER; PTHR24173:SF74; UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 10.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 9..41
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 78..110
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 111..143
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 145..177
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 178..210
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 211..243
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 458..505
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 525 AA; 58629 MW; 0A8044D64D4B498A CRC64;
MDFTEAYSDT CSTVGLAARE GNVKVLRKLL KNGRSVDVAD NRGWMPVHEA AYHNSIECLR
MLIRADSSKN YIKAKTFEGF CALHLAASQG HWKIIQILLE AGADPNATTL EETTPLFLAV
ENGQIDVLRL LLRYGANVNG SHSMCGWNTL HQATFQENAE IIKLLLKKGA NKECQDDFGI
TPLFVAAQYG KLESLSILIS SGANVNCQAL DKATPLFIAA QEGHTECVEL LLSSGADPDL
YCNEDNWQLP IHAAAQMGHT KILDLLIPLT NRVCDTGPNK VSPVYSAVFG GHEECLEMLL
QSGYRPDAQM CLVFGFSSPM CMAFQKDCDF FGIVNILLKY GAQLNELHLA YCLKYERFSV
FRYFLKKCCP LTSWSHISEF ISHAVKAQTK YKEWLPSLLL AGFDPLNLLC STWIDSISDD
ILIFTLEFTN WRRLPPAVEK MLSARASNSS WALQQHIASV PSLTHLCRLE IRSSLKPEHL
RSNSFICQLP LPRSLHDYLL YAEVLRMNEV PELAVIQDGE ISEAT
//
