ID A0A2Y9Q7P0_DELLE Unreviewed; 1192 AA.
AC A0A2Y9Q7P0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2021, sequence version 2.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Ataxin-2 isoform X1 {ECO:0000313|RefSeq:XP_022453571.2};
GN Name=ATXN2 {ECO:0000313|RefSeq:XP_022453571.2};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022453571.2};
RN [1] {ECO:0000313|RefSeq:XP_022453571.2}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022453571.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ataxin-2 family.
CC {ECO:0000256|ARBA:ARBA00007503}.
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DR RefSeq; XP_022453571.2; XM_022597863.2.
DR AlphaFoldDB; A0A2Y9Q7P0; -.
DR STRING; 9749.A0A2Y9Q7P0; -.
DR InParanoid; A0A2Y9Q7P0; -.
DR OrthoDB; 4269134at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd00600; Sm_like; 1.
DR InterPro; IPR009818; Ataxin-2_C.
DR InterPro; IPR045117; ATXN2-like.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR009604; LsmAD_domain.
DR InterPro; IPR047575; Sm.
DR InterPro; IPR025852; SM_dom_ATX.
DR PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR PANTHER; PTHR12854:SF11; ATAXIN-2; 1.
DR Pfam; PF06741; LsmAD; 1.
DR Pfam; PF07145; PAM2; 1.
DR Pfam; PF14438; SM-ATX; 1.
DR SMART; SM01272; LsmAD; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS52002; SM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 99..176
FT /note="Sm"
FT /evidence="ECO:0000259|PROSITE:PS52002"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 970..1052
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..434
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..650
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..673
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 674..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..740
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..763
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..1028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1036..1052
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1192 AA; 128012 MW; 2F456617764C1192 CRC64;
MSLKPQQQQQ QQPAAANARK PGGGGGLLTS PAAAPSPSSS SVSSSSAAAS SSSSSSSSSS
SVAAASAGGG RPGLGRGRNS SKGLPQSTIS FDGIYANMRM VHILTSVVGS KCEVQVKNGG
IYEGVFKTYS PKCDLVLDAA HEKSTESSSG PKREEIMESI LFKCSDFVVV QFKDMDSSYA
RRDAFTDSAI SAKVNGEHKE KDLEPWDAGE LTTSEELEAL ENDVSNGWDP NDMFRYNEEN
YGVVSTYDSS LSSYTVPLER DNSEEFLKRE ARANQLAEEI ESSAQYKARV ALENDDRSEE
EKYTAVQRNS SEREGHNINT RENKYIPPGQ RNREVISWGS GRQNSPRMGQ PGSGSMPSRS
TSHTSDFNPN SGSDQRVVNG GVPWPSPCPS PSSRPPSRYQ SGPNSLPPRA ATPTRPPSRP
PSRPSRPPSH PSAHGSPAPV STMPKRMSSE GPPRMSPKAQ RHPRNHRVSA GRGSISSGLE
FVSHTPPSEA TAPPAARTSP AGGTWSSVVS GVPRLSPKTH RPRSPRQNSI GNTPSGPVLA
SPQAGIIPAE AVAMPVPAAS PTPASPASNR AVTPSLEAKD SRLQDQRQTS SAGNKENMKP
SETSPSFSKA ESKGISPIVS EHRKQIDDLK KFKNDFRLQP SSTSESMDQL LNKNREGEKS
RDLIKDKIEP NAKDSFIENS SNCTSGSSKP SSPSISPSIL NNTEHKRGPE VTSQGVQTSS
PGCKQEKDDK EEKKDAAEQV RKSTLNPNAK EFNPRSFSQP KPSTTPTSPR PQAQPSPSMV
GHQQPTPVYT QPVCFAPNMM YPVPVSPGVQ PLYPIPMTPM PVNQAKTYRA GKVPNMPQQR
QDQHHQSTMM HPASAAGPPI VATPPAYSTQ YVAYSPQQFP NQPLVQHVPH YQSQHPHVYS
PVIQGNARMM APPTHAQPGL VSSSATQYGA HEQTHAMYAC PKLPYNKETS PSFYFAISTG
SLAQQYAHPN ATLHPHTPHP QPSATPTGQQ QSQHGGSHPA PSPVQHHQHQ AAQALHLASP
QQQSAIYHAG LAPTPPSMTP ASNTQSPQNS FPTAQQTVFT IHPSHVQPAY TNPPHMAHVP
QAHVQSGMVP SHPTAHAPMM LMTTQPPGGP QAALAQSALQ PIPVSTTAHF PYMTHPSGEA
CVCRGRRAPQ SILLAQVEWQ AGPVLQAPHL RTSKTRQSVH SRDCDDQFSV RA
//
