ID   A0A2Y9QIC2_DELLE        Unreviewed;      1944 AA.
AC   A0A2Y9QIC2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Anaphase-promoting complex subunit 1 isoform X1 {ECO:0000313|RefSeq:XP_022455017.1, ECO:0000313|RefSeq:XP_022455018.1};
GN   Name=ANAPC1 {ECO:0000313|RefSeq:XP_022455017.1,
GN   ECO:0000313|RefSeq:XP_022455018.1, ECO:0000313|RefSeq:XP_022455019.1,
GN   ECO:0000313|RefSeq:XP_022455020.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022455017.1};
RN   [1] {ECO:0000313|RefSeq:XP_022455017.1, ECO:0000313|RefSeq:XP_022455018.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022455017.1,
RC   ECO:0000313|RefSeq:XP_022455018.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the APC1 family.
CC       {ECO:0000256|ARBA:ARBA00010547}.
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DR   RefSeq; XP_022455017.1; XM_022599309.2.
DR   RefSeq; XP_022455018.1; XM_022599310.2.
DR   RefSeq; XP_022455019.1; XM_022599311.2.
DR   RefSeq; XP_022455020.1; XM_022599312.2.
DR   STRING; 9749.A0A2Y9QIC2; -.
DR   KEGG; dle:111187541; -.
DR   OrthoDB; 180933at2759; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR024990; Apc1.
DR   InterPro; IPR048971; Apc1_3rd.
DR   InterPro; IPR041221; APC1_C.
DR   InterPro; IPR046794; Apc1_MidN.
DR   InterPro; IPR049255; Apc1_N.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR   Pfam; PF12859; ANAPC1; 1.
DR   Pfam; PF21282; APC1_3rd; 1.
DR   Pfam; PF18122; APC1_C; 1.
DR   Pfam; PF20518; Apc1_MidN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          81..203
FT                   /note="Anaphase-promoting complex subunit 1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12859"
FT   DOMAIN          666..985
FT                   /note="Anaphase-promoting complex subunit 1 middle"
FT                   /evidence="ECO:0000259|Pfam:PF20518"
FT   DOMAIN          1617..1702
FT                   /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF21282"
FT   DOMAIN          1736..1895
FT                   /note="Anaphase-promoting complex subunit 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18122"
FT   REGION          319..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          371..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          994..1015
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1944 AA;  216288 MW;  7EF11D1F2EDD7674 CRC64;
     MSNFYEERAT MIAAGDLQEF VPFGRDHCKH HPNALNLQLR QLQPASELWS SDGAAGLVGS
     LQEVTIHEKQ KESWKLRKGV SEIGEEVDYD EELYVAGNMV IWSKGSKSQA LAVYKAFTVD
     SPVQQALWCD FIISQDKSEK DYSSDEVEKC ICILQSSCIN MHSIEGKDYI ASLPFQVANV
     WPTKYGLLFE RSSSSHEVPP GPPREPLPTM FSMLHPLDEI TPLVCKSGSL FGSSRVQYVV
     DHAMKIVFLN TDPSVVMTYD TVQGLHSVWA LRRVKTEEEN VVLKFSEQGG TPQNVATSSS
     LTAHLRSLSR GDSPVASPFQ NYSSIHSQSR SASSPSLHSR SPSISNMAAL SRAHSPALGV
     HSFSGVQRFN LSSHNQSPKR HSISHSPNSN SNGSFLAPET EPIVPELCMD HLWTETITNT
     REKNSQASKV FITSDLCGQK FLCFLVESQL QLRCVKFQES NDKTQLIFGS VTNIQAKDAA
     PVEKIDTMLV LEGSGNLVLY TGVVRVGKVF IPGLPAPSLT MSNTMPRPST PLDSVSTPNP
     LSKLLGSLDE AVLLSPVPEL RDSSKLHDSL YNEDCTFQQL GTYIHSIRDP VHNRVTLELS
     NGSMVRITIP EIATSELVQT CLQAIKFILP KEVAVQMLVK WYSVHSAPGG PSYHSEWNLF
     VTCLMNMMGY NTDRLAWTRN FDFEGSLSPV IAPKKARPSE TGSDDDWEYL LNSDYHQNVE
     SHLLNRSLCL SPLEVSQMKD EDLSQNLSLD SSTLLFTHIP AIFFVLHLIY EELKLNTLMG
     EGIRSLVELL VQLARDLKLE AYVDHYYRDY PALVRTTGQV CTIDQGQTGF MHHPSFFTSE
     PPSIYQWVSS CLKGEGMPPY PYLPVICERS RLVVLSIALY ILGDESSVSD ESSQYLSRIS
     IAPQKSQAEQ EENRFSFRHS TSVSSLAERL VVWMTNVGFA LRDLETLPFG IALPIRDAIY
     HCREQPASDW PEAVCLLIGR QDLSKQACEG NLPKGKSVLS SDVPSGTETE EEDDGMNDMN
     QEVMSLIWSE DLRVQDVRRL LQSAHPVRVN VVQYPELSDH EFIEEKENRL LQLCQRTMAL
     PVGRGMFTLF SYHPVPTEPL PIPKLNLTGR APPRNTTVDL NSGNIDVPPN MTSWASFHNG
     VAAGLKIAPA SQIDSAWIVY NKPKHAELAN EYAGFLMALG LNGHLTKLAT LNIHDYLTKG
     HEMTSIGLLL GVSAAKLGTM DMSITRLLSI HIPALLPPTS TELDVPHNVQ VAAVVGIGLV
     YQGTAHRHTA EVLLAEIGRP PGPEMEYCTD RESYSLAAGL ALGMVCLGHG SNLIGMSDLN
     VPEQLYQYMV GGHRRFQAGM HREKHKSPSY QIKEGDTINV DVTCPGATLA LAMIYLKTNN
     RSIADWLRAP DTMYLLDFVK PEFLLLRTLA RCLILWDDIL PNSKWVDSNV PQIIRENSIS
     LSEIELPCSE DLNLETLSQA HVYIIAGACL SLGFRFAGSE NLSAFNCLHK FAKDFMTYLS
     APNASVTGPY NLETCLSVVL LSLAMVMAGS GNLKVLQLCR FLHMKTGGEM NYGFHLAHHM
     ALGLLFLGGG RYSLSTSNSS IAALLCALYP HFPAHSTDNR YHLQALRHLY VLAAEPRLLV
     PVDVDTNTPC YALLEVTYKG TQWYEQTKEE LMAPTLLPEL HLLKQIKVKG PRYWELLIDL
     SKGTQHLKSI LSKDGVLYVK LRAGQLSYKE DPMGWQSLLA QTVANRNSEA RAFKPETISA
     FTSDPALLSF AEYFCKPTVN MGQKQEILDL FSSVLYECVT QETPEMLPAY IAMDQAVRRL
     GRREMSETSE LWQIKLVLEF FSSRSHQERL QNHPKRGLFM NSEFFPVVKC TIDNTLDQWL
     QAGGDGCVQA YLNGQPCEES QLSMLACFLV YHSVPAPRHL PSIGLEGSTS FAELLFTFKQ
     LKVPVRALLR LAPLLLGNPQ PMLM
//