ID A0A2Y9QIL6_TRIMA Unreviewed; 583 AA.
AC A0A2Y9QIL6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=LOW QUALITY PROTEIN: zinc finger protein 619 {ECO:0000313|RefSeq:XP_023581642.1};
GN Name=LOC101354719 {ECO:0000313|RefSeq:XP_023581642.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023581642.1};
RN [1] {ECO:0000313|RefSeq:XP_023581642.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_023581642.1; XM_023725874.1.
DR AlphaFoldDB; A0A2Y9QIL6; -.
DR KEGG; tmu:101354719; -.
DR InParanoid; A0A2Y9QIL6; -.
DR OrthoDB; 1383805at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47772:SF4; REDUCED EXPRESSION 2-RELATED; 1.
DR PANTHER; PTHR47772; ZINC FINGER PROTEIN 200; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 9.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 34..106
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 221..248
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 249..276
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 277..304
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 305..332
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 333..360
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 361..388
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 389..416
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 417..444
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 445..472
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 473..500
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 583 AA; 66520 MW; 59B2C99B68B146B0 CRC64;
MGLRTMDPGR SIPSLEFRHL PQGLGRILLF QESVTFKDVA VYFTQSQWAS LDPAQRGLYK
EVMLENYANV ASLAEFPFLK PDLILQLERG EAPWGPDPWT LLGEEALRGI CAGDKTKPDI
EAPPPKLNIS EESESPRLIL ARLLMDVPQH PHFKDRVEKP HVYDTGKKTK SKKGDFADLR
AQDGKPTTVD REEIARKLER SRGTSTHLIT KQSLPREQVF YKCGECGRNF SQHSDLHQHQ
RIHTDEKPYQ CKECGKAFRC NSKLSRHQKI HSGEKPYSCQ ECGQAFSQNS HLLQHQKLHS
GEQPYKCKDC GKTFSYNSKL IRHQRIHTGE KPFKCKECGK AFRCSYDCII HERIHTGEKP
YECQECGKRF SSNSVLIQHH RIHTGEKPYK CKECGKAFRR SWVFLQHQRL HTGEKLYKCN
ECWKTFSCSS HFIVHQRIHT GEKPFKCQEC GKAFNQKTTL VQHQRVHTGE KPYECKVCGK
AFKWSASYIQ HQKLHTRKTP VQVIAPSPVE PHCPSEVLSP QPPQCACSAP TIPGSPPSSP
HAVLLPPSMS LFILFPSSEM ATSSPVQIVH FFQDLASPET HSL
//
