ID   A0A2Y9QJC5_TRIMA        Unreviewed;       920 AA.
AC   A0A2Y9QJC5;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Protein FAN isoform X2 {ECO:0000313|RefSeq:XP_023583545.1};
GN   Name=LOC101349528 {ECO:0000313|RefSeq:XP_023583545.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023583545.1};
RN   [1] {ECO:0000313|RefSeq:XP_023583545.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_023583545.1; XM_023727777.1.
DR   AlphaFoldDB; A0A2Y9QJC5; -.
DR   Proteomes; UP000248480; Unplaced.
DR   CDD; cd06071; Beach; 1.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 1.10.1540.10; BEACH domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR000409; BEACH_dom.
DR   InterPro; IPR036372; BEACH_dom_sf.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR023362; PH-BEACH_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR   PANTHER; PTHR13743:SF162; PROTEIN FAN; 1.
DR   Pfam; PF02138; Beach; 1.
DR   Pfam; PF02893; GRAM; 1.
DR   Pfam; PF00400; WD40; 5.
DR   SMART; SM01026; Beach; 1.
DR   SMART; SM00568; GRAM; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF81837; BEACH domain; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50197; BEACH; 1.
DR   PROSITE; PS51783; PH_BEACH; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          189..286
FT                   /note="BEACH-type PH"
FT                   /evidence="ECO:0000259|PROSITE:PS51783"
FT   DOMAIN          290..575
FT                   /note="BEACH"
FT                   /evidence="ECO:0000259|PROSITE:PS50197"
FT   REPEAT          713..743
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          762..803
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          804..845
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          885..920
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          582..601
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        582..597
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   920 AA;  104498 MW;  50F936AADF357F4D CRC64;
     MAFIRKKRQE RQLQLYSKER FSLLLLNLEE YYFEQHTANH IQHKGSPNER KIRGSLKVCS
     KSVIFEPDAI SQPIIKIPLR DCIKIGKHGE NGANRHFAKA KSGGISLIFS QVYFIKEHNI
     VAPYKIERGQ MEYVFELDVS GKVEDVVETL LQLHRASCLD KLGDQTAMIT AILQSRLART
     SFDKNRFQSV SEKLHMECKA EMVAPLVTNP GHVCITDANL YFQPLNGHPK PVVQLTLQDI
     RRIYKRRHSL MPLGLEVFCT EDDLCSDIYL KFYEPQDRDD LYYCIATYLE NHVAKHTAES
     YMLQWQRGHL SNYQYLLHLN NLADRSCNDL SQYPVFPWII NDYYSSTLDL SNPETFRDLS
     KPVGALNKER LERLLTRYRE MPEPKFMYGS HYSSPGYVLF YLVRIAPEYM LCLQNGRFDN
     ADRMFNSIAE TWKNCLDGAT DFKELIPEFY GDDVSFLVNS LKLDLGKRQG GKMVDDVELP
     PWAASPEDFL RKSKDALESN YVSEHLHEWI DLIFGYKQKG SDAVGAHNVF HPLTYEGGVD
     LNSIEDPDEK VAMLTQILEF GQTPKQLFVT PHPRRITTKF KSLSQTSSDN ASMADSPVSA
     GEESFEDLTE ESKTLAWTNI TKLQLHEHYK IHKEAVTGIA VSCNGCSIFT TSQDSTLKMF
     SKESKMLQRS ISFSNMALSS CLLLPGDATV LSSSWDNNVY FYSIAFGRHQ DTLMGHDDAV
     SKICWHDNRL YSASWDSTVK VWSGIPAETP CTRRHHFHLL AELEHDVGVD TISLNAASTL
     LVSGTKEGTV SIWDLTTATM LHQIPCHSGT VYDTAFSPDS RHVLSTGEDG CLNIIDVQTG
     MLISSLTSEE PQRCFIWDGN SVLSGSQSGE LLVWDLLGAK LSERIQGHTG AVTCIWMNEQ
     CSSIITGGDD RQIMFWKLQY
//