ID A0A2Y9QJV8_TRIMA Unreviewed; 310 AA.
AC A0A2Y9QJV8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Homer protein homolog 2 isoform X3 {ECO:0000313|RefSeq:XP_023581741.1};
GN Name=LOC101360814 {ECO:0000313|RefSeq:XP_023581741.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023581741.1};
RN [1] {ECO:0000313|RefSeq:XP_023581741.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_023581741.1; XM_023725973.1.
DR AlphaFoldDB; A0A2Y9QJV8; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0035256; F:G protein-coupled glutamate receptor binding; IEA:InterPro.
DR Gene3D; 1.20.5.1700; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045027; Homer.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR10918; HOMER; 1.
DR PANTHER; PTHR10918:SF2; HOMER PROTEIN HOMOLOG 2; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50229; WH1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 1..111
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT REGION 70..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 129..274
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 80..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 310 AA; 35753 MW; 14742176F1EF5C64 CRC64;
MGEQPIFTTR AHVFQIDPST KKNWVPASKQ AVTVSYFYDV TRNSYRIISV DGAKFAEKFQ
EVKEAARLAR DRSQEKIETS SNHSQESGCE TPSSTQASSV NGTDDEKASH TGPADTHLKS
ENDKLKIALT QSAANVKKWE IELQTLRESN ARLTTALQES AASVEQWKKQ FSICRDENDR
LRNKIDELEE QCSEINKEKE KNTQLKHRIE ELESELREKE TELKDLRKQS EIIPQLMSEC
EYVSEKLEAA ERDNQNLEDK VRCLKTDIEE SKYRQRHLKV ELKNFLEVLD GKIDDLHDFR
RGLSKLSSDN
//
