ID   A0A2Y9R2P0_TRIMA        Unreviewed;      1304 AA.
AC   A0A2Y9R2P0;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=LOW QUALITY PROTEIN: von Willebrand factor A domain-containing protein 3B {ECO:0000313|RefSeq:XP_023587751.1};
GN   Name=LOC101347382 {ECO:0000313|RefSeq:XP_023587751.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023587751.1};
RN   [1] {ECO:0000313|RefSeq:XP_023587751.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_023587751.1; XM_023731983.1.
DR   STRING; 127582.A0A2Y9R2P0; -.
DR   KEGG; tmu:101347382; -.
DR   InParanoid; A0A2Y9R2P0; -.
DR   OrthoDB; 5396918at2759; -.
DR   Proteomes; UP000248480; Unplaced.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR032770; DUF4537.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR46785; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B; 1.
DR   PANTHER; PTHR46785:SF1; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B; 1.
DR   Pfam; PF15057; DUF4537; 1.
DR   Pfam; PF13768; VWA_3; 2.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT   DOMAIN          503..679
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          713..773
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1005..1027
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1193..1304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        716..755
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1213..1229
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1231..1251
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1252..1276
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1304 AA;  146692 MW;  0038F0B0F9BD4188 CRC64;
     METSGSVSVV SEQQLQKPEG TRNTKTGLAE QSLISSEKWL QLHGLKSNRL TLKQILPQIG
     FPRCKDYLAS LGRPVASRCA DGLFPQFCRA YNLTAKSELI HQFVEYLTQA AESYKQRMEW
     LTSRSRQVFG VILEQRVTMV LDFGDMLEEE LKLCQEALVM ALQEQVAHVS KFNMIRVSQE
     PVKWQENATL VTEQSIAAAI SWVEKLTFDL VVSQASCLDA LLEAGKDKTI ESIYYFVVGD
     IPEESKELLL QRVLEIPCPV CTVSFNARGE GTITFLKDLS AKSHGRFHAF AERTECVQFP
     APTTKDGGSG ITWNSRRLKG KPPPGAGVRE DVFLIWKEVE EARSTLAQLQ SLVTELPKSD
     RDKTACESGA ASVENESNPE DTWDSRKWLQ KYGLKAQKLS FYDVLADCSF RHIDGVVDIK
     AKPANESVKT SAVIIKKTVH ARYCSRFLHA PWKDGSLVHV HVTKEKCRWY RERIHSLLAQ
     IERRIEWLQD GSQMLFGKVL HDCVYILIDA SHSMKGKLDL VKDKIIQLIQ EQLKYKSKFN
     FVTFDAQAVA WSEKLAEINE DNLERAQSWV RGIEVGSSTN TLNALQIAFA DKETQVIYLL
     TDGRPDQPPE VIIDQVKVSH KIPVYTISFN YNDEIANGFL KELACLTGGE FHFYNFGGKD
     PYPPETDQNE DLTLLVKEME QGRRDLEKMQ DLYSESLIMD WWYNGEKEGE NKHQKEISSL
     VSTSEKCAKP QPDVESTETS SPSASKGQGG LPNQRSQRKK VLHAEPTKTS LLRSQMSTLR
     SSACCDRKDG LSSCSSRNVA SSDMRVSLLT DDYPDDRSLE RSTREGSQVY DQDSLDMSSA
     NWLKTHGLVA KKLTIMDALS VTAVPHTTTY IPVLDKHVAS KVFDEVFPLA RVCNGTNKMT
     LINPQGVKLD IYKQKVEQAI RSYERRLNKI VWRALSPEEK EKLDADKPMR YLENKVALNE
     ALERLNWPIS LKELSLLENE ILAGKMYIQQ AMELQEAAKK ENYVSRALGE QQKPQGNPTK
     KSKSRRLDPL KGQKVIARCE ENGFYFPGVV KKCVSPTHAL VGFRYGDTKV VPTSYITPVG
     GAMPCPMLQV GDYVFAKIVI PKGFDFYVPA IVVALPNQDV PEDKFYTVLK CNNRREFCPR
     SALIKISQNK YAISCSQIKS PPIQEDPKVL EAEKKNSAFT IWPLKDIDAG DLKELKQNHG
     RKKKPAKKVY PQERMSSDSN SSSCDSQESY PKGHLKPKAG REQRRLSPEH PDASFENSTQ
     GPQPRPLDSA RHAVTTTPSP XAAPPCXLIA THGSKGLSTI AEKT
//