ID A0A2Y9R321_TRIMA Unreviewed; 400 AA.
AC A0A2Y9R321;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ETS-related transcription factor Elf-3 {ECO:0000313|RefSeq:XP_023586039.1};
GN Name=LOC101342160 {ECO:0000313|RefSeq:XP_023586039.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023586039.1};
RN [1] {ECO:0000313|RefSeq:XP_023586039.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_023586039.1; XM_023730271.1.
DR AlphaFoldDB; A0A2Y9R321; -.
DR STRING; 127582.A0A2Y9R321; -.
DR KEGG; tmu:101342160; -.
DR InParanoid; A0A2Y9R321; -.
DR OrthoDB; 3686750at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd08537; SAM_PNT-ESE-1-like; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042693; Elf-3_PNT.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR003118; Pointed_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF13; ETS-RELATED TRANSCRIPTION FACTOR ELF-3; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF02198; SAM_PNT; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SMART; SM00251; SAM_PNT; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR PROSITE; PS51433; PNT; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 46..132
FT /note="PNT"
FT /evidence="ECO:0000259|PROSITE:PS51433"
FT DOMAIN 302..384
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 212..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 44608 MW; 5DD8B249B10031E3 CRC64;
MAATCEISNV FSNYFSAMYS SEDPTLVSAP PAANFGADDV VLTLSNTQMP LQGTEKASWS
GEQPQFWSKA QVLDWISYQV EKNKYDASSI DFSRCDMDGA TLCNCALEEL RLVFGPLGDQ
LHAQLQDLSE SRLLVRGGLT SKQAASSSDE LSWIIEPLEK DGMSDELSWI IELLEKDGMA
FQETLGDMGP LDQASPFVQE LLEDCPYYPS SYGAGAPSPG SSDVSTAGTG TPQSSHSSDS
GGSDVDLDPT DSSKLFPTDG FPDYKKGDPK HGKRKRGRPR KLSKESRECL EGKKSKHAPR
GTHLWEFIRD ILIHPELNEG LMKWENRHEG VFKFLRSEAV AQLWGQKKKN SSMTYEKLSR
AMRYYYKREI LERVDGRRLV YKFGKNSSGW KEEEVAGSRN
//
