ID A0A2Y9R6J8_TRIMA Unreviewed; 789 AA.
AC A0A2Y9R6J8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Zinc finger protein 709-like isoform X1 {ECO:0000313|RefSeq:XP_023589066.1};
GN Name=LOC101346579 {ECO:0000313|RefSeq:XP_023589066.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023589066.1};
RN [1] {ECO:0000313|RefSeq:XP_023589066.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC {ECO:0000256|ARBA:ARBA00003767}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_023589066.1; XM_023733298.1.
DR AlphaFoldDB; A0A2Y9R6J8; -.
DR InParanoid; A0A2Y9R6J8; -.
DR OrthoDB; 3041019at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 20.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23226:SF317; RCG31665-RELATED; 1.
DR PANTHER; PTHR23226; ZINC FINGER AND SCAN DOMAIN-CONTAINING; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 16.
DR Pfam; PF13912; zf-C2H2_6; 2.
DR Pfam; PF13465; zf-H2C2_2; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 20.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 13.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 19.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 21.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 4..83
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 144..171
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 198..225
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 226..253
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 254..281
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 282..309
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 310..337
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 338..365
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 366..393
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 394..421
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 422..449
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 450..477
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 478..505
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 506..533
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 534..561
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 562..589
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 590..617
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 618..645
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 646..673
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 674..701
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 702..729
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 730..757
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 789 AA; 92889 MW; DCBEE15E64B4DE0F CRC64;
MESVVFEDVA VDFTLEEWAL LDPAQRKLYK DVMLETFRNL ASLDDETPFK ANESVSQQDI
YVKKLSKEHK TTKFTRSDSQ TSILAKIWEG LSIEDQQKNQ AIPLRNHMIE RDCEINDRNQ
CGETFCQILN LNLFKENPIL LNPYECSEYG KLSMHHSSLK RHIESDTGHK PYQEYMQTCS
CPSDIKMHEQ SHGAGRPYAC KLCGKTFSYL QSFQSHEGTY TKEKPYECKQ CRKAFSWPIS
LRRHMRRHTG EKPYECNQCR KAFSWPISLK RHVRVHTGEK PYECHQCGKA FKWPLSLRIH
MSTHTGEKHH ECKQCGKAFS WPVYLRAHMR THSVEKPYEC NQCGKAFKWP LSLRTHMSIH
TRDKLYECKH CGKVFSWPIH LEAHMRMHSN EKPYECKQCG KAFKWPLSLR AHMTTHTGEK
PYECKQCKKA FSQLSYLREH VRMHTGKKPY DCKECGKMFK WPSSLRKHMR LHTGEKPYEC
KECGKAFNWP ISLRAHMRIH SGEKPYECKQ CGKAFNWAMS LRTHMSIHTG EKPYECKQCE
KAFNCPKHLR EHMRTHSGEK PYECKQCRKA FSYLQNLRRH ERTHSKEKLY ECKQCGKAFS
QLSYLQGHVR MHTGEKPYVC KECGKAFQWP SFLSNHMRVH SGEKPYECKQ CGKAFNWPIS
LEAHMKTHSG EKPYECSQCG KTFKWPLSLR THMSTHTGEK PYECKQCGKA FSQLSYLRGH
LRMHTGEKPY VCKECGKAFK SPSSLPIHMR IHTGEKPYEF YQYLNVCDLE GRSEEAIREI
LEPQYRETD
//
