ID A0A2Y9R765_TRIMA Unreviewed; 329 AA.
AC A0A2Y9R765;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=26S proteasome regulatory subunit 4 {ECO:0000313|RefSeq:XP_023587423.1};
GN Name=LOC101341654 {ECO:0000313|RefSeq:XP_023587423.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023587423.1};
RN [1] {ECO:0000313|RefSeq:XP_023587423.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914}.
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DR RefSeq; XP_023587423.1; XM_023731655.1.
DR STRING; 127582.A0A2Y9R765; -.
DR KEGG; tmu:101341654; -.
DR InParanoid; A0A2Y9R765; -.
DR OrthoDB; 1707207at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF24; 26S PROTEASOME REGULATORY SUBUNIT 4; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942,
KW ECO:0000313|RefSeq:XP_023587423.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 145..279
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 36761 MW; 9761F843657FDD3B CRC64;
MEEEFIRNQE QMKPLEEKQE EERSKVDDLR GTPMSVGTLE EIIDDNHAIV STSVGSEHYV
SILSFVDKDL LEPGCSVLLN HKVHAVIGVL MDDTDPLVTV MKVEKAPQET YADIGGLDNQ
IQEIKXXXXX XXXXXEYYEE MGIKPPKGVI LYGPPGTGKT LLAKAVANQT SATFLRVVGS
ELIQKYLGDG PKLVRELFRV AEEHAPSIVF IDEIDAIGTK RSGQGVTRTF LPAGRIDRKI
EFPLPDEKTK KRIFQIHTSR MTLADDVTLD DLIMAKDDLS GADIKAICTE AGLMALRERR
MKVTNEDFKK SKENVLYKKQ EGTPEGLYL
//
