ID   A0A2Y9RA63_TRIMA        Unreviewed;      1067 AA.
AC   A0A2Y9RA63;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Myosin phosphatase Rho-interacting protein isoform X3 {ECO:0000313|RefSeq:XP_023591327.1};
GN   Name=LOC101354769 {ECO:0000313|RefSeq:XP_023591327.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023591327.1};
RN   [1] {ECO:0000313|RefSeq:XP_023591327.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_023591327.1; XM_023735559.1.
DR   AlphaFoldDB; A0A2Y9RA63; -.
DR   Proteomes; UP000248480; Unplaced.
DR   CDD; cd13275; PH_M-RIP; 1.
DR   CDD; cd01236; PH_RIP; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039597; M-RIP_PH.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR17271:SF9; MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR17271; PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00169; PH; 2.
DR   SMART; SM00233; PH; 2.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT   DOMAIN          43..150
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          427..523
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          152..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          253..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          355..421
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          525..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          690..713
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          718..745
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          774..917
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          948..1014
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        173..197
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..386
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        526..549
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        550..583
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        615..638
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1067 AA;  121185 MW;  CF51E38376EB064F CRC64;
     MSAAKENPCR KFQANIFNKS KCQNCFKPRE SHLLNDEDLS QAKPIYGGWL LLAPDGTDFD
     NPVHRSRKWQ RRFFILYEHG LLRYALDEMP TTLPQGTINM NQCTDVVDGE GRTGQKFSLC
     ILTPEKEHFI RAENKEIISG WLEMLMVYPR TNKQNQKKKR KVEPPTPQEP GPAKMAVTSS
     SSIPSAEKVP TTKSTLWQEE MRAKDQPDGR SLSPAPSPGQ SQPPAASSLR EPGLESREGP
     RPTCRMICSI SLNSLDTASP PPAHLDSGSA GGRGAERLGH AFAFKASRQY ATLADIPKAI
     RISHREAFQV EKRRLERRTR AHSPGREEVA RLFGNERRRS QVIEKFEALD IEKAEHMETS
     APAGPTPTSD TRQGRTEKRV FPRKRDLTAE APTAPLLDVP APPLSPHRRA KSLDRRSTEP
     SMTPDLLNFK KGWLTKQYED GQWKKHWFVL ADQSLRYYRD SVAEEAADLD GEIDLATCYS
     VTEYPVQRNY GFQIHTKEGE FALSAMTSGI RRNWIQTIMK HVHPTTAPDV TSSLPEEKSK
     SGSPETCPRP SEKQESDPGE PDPEQRRSRA RERRREGRSK TFDWAEFRPI QQALAQERAG
     ATGPCDAQEP GCPEADPGEL ERERTRRREE RRRRFGALDT VDGPGGTDDA ILRMEVDRSP
     SLPVTSDLKT QSVHVEIEQR WHQVETTPLR EEKQVPISPL HLSPSEDGSN RLPTHELTSL
     LEKELEQSQK EASELLEQNR LLQDQLRVAL GREQSAREGY VLQATCERGF AAMEETHQKK
     IEDLQRQHQR ELEKLREEKD RLLAEETAAT ISAIEAMKNA HREEMERELE KSQRSQISSI
     NSDIEALRRQ YLEELQSVQR ELEVLSEQYS QKCLENAHLA QALEAERQAL RQCQRENQEL
     NAHNQELNNR LAAEITRLRT LLTGDGGGEA GGSPLTQGKD AYELEVLLRV KESEIQYLKQ
     EISSLKDELQ TALRDKKYAS DKYKDIYTEL SIVKAKADCD ISRLKEQLKA ATEALGEKSP
     ENTTVSGYDI MKSKSNPDFL KKDRSCVSRQ LRNIRSKSVI EQVSWDN
//