ID A0A2Y9RGH2_TRIMA Unreviewed; 977 AA.
AC A0A2Y9RGH2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=General transcription factor II-I isoform X6 {ECO:0000313|RefSeq:XP_023591064.1};
GN Name=LOC101342343 {ECO:0000313|RefSeq:XP_023591064.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023591064.1};
RN [1] {ECO:0000313|RefSeq:XP_023591064.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_023591064.1; XM_023735296.1.
DR AlphaFoldDB; A0A2Y9RGH2; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 3.90.1460.10; GTF2I-like; 6.
DR InterPro; IPR004212; GTF2I.
DR InterPro; IPR036647; GTF2I-like_rpt_sf.
DR InterPro; IPR016659; TF_II-I.
DR PANTHER; PTHR46304:SF2; GENERAL TRANSCRIPTION FACTOR II-I; 1.
DR PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02946; GTF2I; 6.
DR PIRSF; PIRSF016441; TF_II-I; 1.
DR SUPFAM; SSF117773; GTF2I-like repeat; 6.
DR PROSITE; PS51139; GTF2I; 6.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 241..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 794..815
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..977
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..815
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 977 AA; 109915 MW; EC00C52E69C89D36 CRC64;
MAQVAVSALP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE
RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM NKMKSTTQAN RMSVDAVEIE TLRKTVEDYF
CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI
SFIIKRPFLE PKKHLGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGM SLEMAAVTVK
EESEDPDYYQ YNIQAGPSET DDVDEKLPLS KSLQGSHHSS EGNEGTEMEV PAEDSTQHVP
SETSEDPEVE VTIEDDDYSP PTKRPKSSEP PQPPVTEPAN AGKRKVREFN FEKWNARITD
LRKQVEELFE RKYAQAIKAK GPVTIPYPLF QSHVEDLYVE GLPEGIPFRR PSTYGIPRLE
RILLAKERIR FVIKKHELLN STREDLQLDK PASGVKEEWY ARITKLRKMV DQLFCKKFAE
ALGSTEAKAV PYQKFEAHPN DLYVEGLPEN IPFRSPSWYG IPRLEKIIQV GNRIKFVIKR
PELLTHSTTE VTQPRTNTPV KEDWNVRITK LRKQVEEIFN LKFAQALGLT EAVKVPYPVF
ESNPEFLYVE GLPEGIPFRS PTWFGIPRLE RIVRGSNKIK FVVKKPELVI SYLPPGMASK
INTKALQSPK RPRSPGSNSK VPEIEVTVEG PNNNSPQTSA VRAPTQTNGS NVPFKPRGRE
FSFEAWNAKI TDLKQKVENL FNEKCDFYVE GLPEGVPFRR PSTFGIPRLE KILRNKAKIK
FIIKKPEMFE TAIKESAASS KSPPRKLNSS PNVNTTASGV EDLNIIQVTI PDDDNERLSK
VEKARQLREQ VNDLFSRKFG EAIGMGFPVK VPYRKITINP GCVVVDGMPP GVSFKAPSYL
EISSMRRILD SAEFIKFTVI RPFPGLVINN QLADQSESEG PVIQESAEPS QLEVPTTEEI
KDTDGSSQIK QEPDATW
//
