ID   A0A2Y9RI50_TRIMA        Unreviewed;       487 AA.
AC   A0A2Y9RI50;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Succinate-semialdehyde dehydrogenase, mitochondrial {ECO:0000256|ARBA:ARBA00019842};
DE            EC=1.2.1.24 {ECO:0000256|ARBA:ARBA00013051};
DE   AltName: Full=NAD(+)-dependent succinic semialdehyde dehydrogenase {ECO:0000256|ARBA:ARBA00030806};
GN   Name=LOC101343803 {ECO:0000313|RefSeq:XP_023594117.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023594117.1};
RN   [1] {ECO:0000313|RefSeq:XP_023594117.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_023594117.1; XM_023738349.1.
DR   AlphaFoldDB; A0A2Y9RI50; -.
DR   Proteomes; UP000248480; Unplaced.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00171; Aldedh; 2.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT   DOMAIN          75..244
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   DOMAIN          247..482
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   487 AA;  52505 MW;  4FB027808CECA225 CRC64;
     MATCFQLRGC GAQRLSLLPL GRGPCPCAGY LGLSTQPKPG LALLRGYAQG PAGLPPALLR
     TDGFVGGRWL PARAVFPVYD PASGAELGKV ADCGAPEARA AVRAAYEAFC SWREVSAKER
     SSLLRKWYDL MIKNKEDLAK IITAENGKPL KEAQGEILYS ALFLEWFSEE ARRIYGDIIY
     TPAKDKRSLV LKQPVGVATV ITPWNFPSAM ITRKVGAALA AGCTVVVKPA EDTPLSALAL
     AEILLHYAAD SVKRVSMELG GHAPFIVFDS ANVDQAVAGA MASKFRNSGQ TCVCSNRFLV
     QRGIHDSFVK KLAEAIKRDL RVGNGFEEGT TQGPLINEKA IEKVEKHVSD AVSKGATIET
     GGKRHRFGKN FFEPTLLSNV TRDMLCSHEE TFGPLAPVMK FDTEEEAVAI ANAADVGLAG
     YFYSQDPAQI WRVAEQLEVG MVGVNEGLIS TVECPFGGVK QSGLGREGSK YGIDEYLELK
     YVCYGGL
//