ID   A0A2Y9RJ65_TRIMA        Unreviewed;       271 AA.
AC   A0A2Y9RJ65;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Transmembrane protein 192 {ECO:0000256|ARBA:ARBA00014635};
GN   Name=LOC111821834 {ECO:0000313|RefSeq:XP_023593616.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023593616.1};
RN   [1] {ECO:0000313|RefSeq:XP_023593616.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Late endosome {ECO:0000256|ARBA:ARBA00004603}.
CC       Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM192 family.
CC       {ECO:0000256|ARBA:ARBA00006314}.
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DR   RefSeq; XP_023593616.1; XM_023737848.1.
DR   AlphaFoldDB; A0A2Y9RJ65; -.
DR   STRING; 127582.A0A2Y9RJ65; -.
DR   KEGG; tmu:111821834; -.
DR   InParanoid; A0A2Y9RJ65; -.
DR   OrthoDB; 2905352at2759; -.
DR   Proteomes; UP000248480; Unplaced.
DR   GO; GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029399; TMEM192.
DR   PANTHER; PTHR31592; TRANSMEMBRANE PROTEIN 192; 1.
DR   PANTHER; PTHR31592:SF1; TRANSMEMBRANE PROTEIN 192; 1.
DR   Pfam; PF14802; TMEM192; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        48..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        139..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   271 AA;  30490 MW;  3496734E3102BBD4 CRC64;
     MAAAGRLEDG SLDLTQSIED HPLMDAPLLP HHSLHAHFRP RFHPVPRVII AHLLLLIHVV
     FVILAFLTGV FCSYPNPHED KCPGNYTNPL KVQTVIILGK VILWTLHVLL ERYVQCHHSD
     VRNQGYNTIY GSTSHLKRLA LNGYSSGNTA LLLILCIQHS FPQPSKLCLD FILSVLALEL
     ICSLTCLLMY TVKIRKFNKT KPRLDVLEEE KIYAYPSSIN SETGFRTISS LEEIVEKQGD
     IIVYLKRHNT PLSKRLLALS SSDLGSQPGR V
//