ID A0A2Y9RQ12_TRIMA Unreviewed; 711 AA.
AC A0A2Y9RQ12;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Cytoplasmic polyadenylation element-binding protein 3 isoform X3 {ECO:0000313|RefSeq:XP_023595766.1};
GN Name=LOC101361730 {ECO:0000313|RefSeq:XP_023595766.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023595766.1};
RN [1] {ECO:0000313|RefSeq:XP_023595766.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM CPEB family.
CC {ECO:0000256|ARBA:ARBA00010347}.
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DR RefSeq; XP_012413395.1; XM_012557941.1.
DR RefSeq; XP_023595766.1; XM_023739998.1.
DR AlphaFoldDB; A0A2Y9RQ12; -.
DR GeneID; 101361730; -.
DR OrthoDB; 5395046at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR CDD; cd19757; Bbox1; 1.
DR CDD; cd12724; RRM1_CPEB2_like; 1.
DR CDD; cd12726; RRM2_CPEB2_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR InterPro; IPR032296; CEBP_ZZ.
DR InterPro; IPR038446; CEBP_ZZ_sf.
DR InterPro; IPR034819; CPEB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR PANTHER; PTHR12566:SF7; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3; 1.
DR Pfam; PF16366; CEBP_ZZ; 1.
DR Pfam; PF16367; RRM_7; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 454..541
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 562..640
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..98
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..189
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 711 AA; 77633 MW; A19838FA5560C0C1 CRC64;
MQDDLLMDKS KTQPQPQQQR QQQQPQPEPS AAEAPSTPLS SETPKPEDSS AVPALSPAAA
PPAPNGPDKM QMESPLLPGL SFHQPPQQPP PPQEPAAPGA SLSPSFGSTW STGTTNAVED
SFFQGITPVN GTMLFQNFPH HVNPVFGGTF SPQIGLAQTQ HHQQPPPAPQ SAQPAQPPQP
QPPQQRRSPA SPSQAPYAQR SAAAAYGHQP IMTSKPSSSS AAVAAAAAAA ASSASSSWNT
HQSVNAAWSA PSNPWGGLQA GRDPRRAVGV GVGVGVGVPS PLNPISPLKK PFSSNVIAPP
KFPRAAPLTS KSWMEDNAFR TDNGNNLLPF QDRSRPYDTF NLHSLENSLM DMIRTDHEPL
KGKHYPPSGP PMSFADIMWR NHFAGRMGIN FHHPGTDNIM ALNTRSYGRR RGRSSLFPFE
DAFLDDSHGD QSLSSGLSSP TRCQNGERVE RYSRKVFVGG LPPDIDEDEI TASFRRFGPL
VVDWPHKAES KSYFPPKGYA FLLFQEESSV QALIDACLEE DGKLYLCVSS PTIKDKPVQI
RPWNLSDSDF VMDGSQPLDP RKTIFVGGVP RPLRAVELAM IMDRLYGGVC YAGIDTDPEL
KYPKGAGRVA FSNQQSYIAA ISARFVQLQH NDIDKRVEVK PYVLDDQMCD ECQGTRCGGK
FAPFFCANVT CLQYYCEYCW ASIHSRAGRE FHKPLVKEGG DRPRHVPFRW S
//
