ID A0A2Y9RQ17_TRIMA Unreviewed; 698 AA.
AC A0A2Y9RQ17;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Cytoplasmic polyadenylation element-binding protein 3 isoform X4 {ECO:0000313|RefSeq:XP_023595771.1};
GN Name=LOC101361730 {ECO:0000313|RefSeq:XP_023595771.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023595771.1};
RN [1] {ECO:0000313|RefSeq:XP_023595771.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM CPEB family.
CC {ECO:0000256|ARBA:ARBA00010347}.
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DR RefSeq; XP_023595771.1; XM_023740003.1.
DR AlphaFoldDB; A0A2Y9RQ17; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR CDD; cd19757; Bbox1; 1.
DR CDD; cd12724; RRM1_CPEB2_like; 1.
DR CDD; cd12726; RRM2_CPEB2_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR InterPro; IPR032296; CEBP_ZZ.
DR InterPro; IPR038446; CEBP_ZZ_sf.
DR InterPro; IPR034819; CPEB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR PANTHER; PTHR12566:SF7; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3; 1.
DR Pfam; PF16366; CEBP_ZZ; 1.
DR Pfam; PF16367; RRM_7; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..698
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015884567"
FT DOMAIN 441..528
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 549..627
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 24..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..116
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..207
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 75996 MW; 3C838A0E310C45D5 CRC64;
MITLTITRLF FPVSAAQTMQ DDLLMDKSKT QPQPQQQRQQ QQPQPEPSAA EAPSTPLSSE
TPKPEDSSAV PALSPAAAPP APNGPDKMQM ESPLLPGLSF HQPPQQPPPP QEPAAPGASL
SPSFGSTWST GTTNAVEDSF FQGITPVNGT MLFQNFPHHV NPVFGGTFSP QIGLAQTQHH
QQPPPAPQSA QPAQPPQPQP PQQRRSPASP SQAPYAQRSA AAAYGHQPIM TSKPSSSSAA
VAAAAAAAAS SASSSWNTHQ SVNAAWSAPS NPWGGLQAGR DPRRAVGVGV GVGVGVPSPL
NPISPLKKPF SSNVIAPPKF PRAAPLTSKS WMEDNAFRTD NGNNLLPFQD RSRPYDTFNL
HSLENSLMDM IRTDHEPLKG RMGINFHHPG TDNIMALNSR SSLFPFEDAF LDDSHGDQSL
SSGLSSPTRC QNGERVERYS RKVFVGGLPP DIDEDEITAS FRRFGPLVVD WPHKAESKSY
FPPKGYAFLL FQEESSVQAL IDACLEEDGK LYLCVSSPTI KDKPVQIRPW NLSDSDFVMD
GSQPLDPRKT IFVGGVPRPL RAVELAMIMD RLYGGVCYAG IDTDPELKYP KGAGRVAFSN
QQSYIAAISA RFVQLQHNDI DKRVEVKPYV LDDQMCDECQ GTRCGGKFAP FFCANVTCLQ
YYCEYCWASI HSRAGREFHK PLVKEGGDRP RHVPFRWS
//
