ID   A0A2Y9RZA4_TRIMA        Unreviewed;       492 AA.
AC   A0A2Y9RZA4;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Interferon alpha/beta receptor 1 isoform X3 {ECO:0000313|RefSeq:XP_023597073.1};
GN   Name=LOC101361715 {ECO:0000313|RefSeq:XP_023597073.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023597073.1};
RN   [1] {ECO:0000313|RefSeq:XP_023597073.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC       Lysosome {ECO:0000256|ARBA:ARBA00004371}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_023597073.1; XM_023741305.1.
DR   AlphaFoldDB; A0A2Y9RZA4; -.
DR   Proteomes; UP000248480; Unplaced.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR   PANTHER; PTHR20859:SF54; INTERFERON ALPHA_BETA RECEPTOR 1; 1.
DR   PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR   Pfam; PF09294; Interfer-bind; 2.
DR   Pfam; PF01108; Tissue_fac; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 4.
DR   PROSITE; PS50853; FN3; 1.
PE   4: Predicted;
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_023597073.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   TRANSMEM        369..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          264..365
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          453..492
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        463..492
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   492 AA;  56195 MW;  0BE6D3DB0C7D68F1 CRC64;
     MHNWIELPGC QYITGTTCDF SSVKLSVFEK IQLRIRAEKG NRTSPWHEVG SFIPFRKAQI
     GPPKVHLKAE DKAIIVNISP PGTKDSLMWA MDILSFTYSV VIWKNSSSVD ERTETVYPGG
     KIYKLSPETT YCLKVKARLR LHRKVGSYSP VYCVNTTVEN KLPSPENIEV DVKDQSYVLK
     WDYTYENMTF QAQWLRAYFK KILGNHSDKW QQIPGCENVR ATQCVFPQKV FSKGAYFLRV
     QASDGNKTSF WSEEKRLDTE MQTVILPPVI SMKSVDNSLH IYIGAPRETE NKSTSQHYPL
     IYEIIFWENT SNAERKILQK KTDFIVPNLQ PLTVYCVKAR AVIEDEKWNK SSVFSDILCE
     KTKPGNTSIT WIIAGVCTAL FSIPVAIYVV KGLLRCINYV FFPSCKPPPN IDQCFSEQSL
     KNLLLSASEE QTERCFIIEN SYSLVTVEET SQVDEDHKQY SSQTSRDSGN YSNEDENSGS
     KTSRELLQQG LV
//