ID A0A2Y9RZU3_TRIMA Unreviewed; 1115 AA.
AC A0A2Y9RZU3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Scavenger receptor cysteine-rich type 1 protein M130 {ECO:0000313|RefSeq:XP_023597283.1};
GN Name=LOC101360710 {ECO:0000313|RefSeq:XP_023597283.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023597283.1};
RN [1] {ECO:0000313|RefSeq:XP_023597283.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_023597283.1; XM_023741515.1.
DR AlphaFoldDB; A0A2Y9RZU3; -.
DR STRING; 127582.A0A2Y9RZU3; -.
DR KEGG; tmu:101360710; -.
DR InParanoid; A0A2Y9RZU3; -.
DR OrthoDB; 5403281at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 9.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 9.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 9.
DR SUPFAM; SSF56487; SRCR-like; 9.
DR PROSITE; PS00420; SRCR_1; 4.
DR PROSITE; PS50287; SRCR_2; 9.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_023597283.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1044..1065
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..151
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 158..258
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 265..365
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 372..472
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 477..577
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 582..682
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 718..818
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 823..925
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 928..1028
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 76..140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 89..150
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 120..130
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 183..247
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 196..257
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 227..237
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 290..354
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 303..364
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 334..344
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 397..461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 410..471
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 441..451
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 502..566
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 515..576
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 546..556
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 607..671
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 620..681
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 651..661
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 743..807
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 756..817
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 787..797
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 863..924
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 894..904
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 953..1017
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 966..1027
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 997..1007
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 1115 AA; 120363 MW; 1573B621BA1C64D9 CRC64;
MDKPKMVLLE DSGSADFRRC FVRLSPFAIA LVSLLSACFI TISLGETEKQ LRLVAGENRC
TGRVEVKVNE EWGTVCNNGW DMDDVSVICG QLGCPTVIKA TGWTNSSAGS GRIWMEHVSC
QGNESALWDC KHDGWGKNNC THQQDAGVTC SDGSDLEMRL VNGGNRCSGR IEVKFQGQWG
TVCDDNLNID FASVVCKQLE CGSAVSFSGS ANFGEGSGPI WFDDLVCHGN ESALWNCKHQ
GWGKHNCDHA EDAGVICLEG ADLTMRLVDG VTECSGRLEV KFQGQWGTVC DDGWDSNDAT
VVCGQLGCPT AVTGIGRVNA SEGSGPIWLD SVACKGHELA LWQCRHQEWG KHYCNHNEDA
GVTCSDGSDL ELRLIGGGSR CAGTVEVKIQ NLLGKVCDRN WGLKEASVVC RQLGCGSVRK
TSYQTYSKVK ATNTWLFVSS CEGNETSLWD CKNWQWGGLP CDPYEEAKIT CSAHREPRLV
GGDIPCSGRV EVKLGDTWGT VCDSDFSLEA ASVLCRELQC GTVISILGGA HFGEGSGQIW
AEEFQCQGDE SHLSLCPVAP RPDGTCSHSR DVGVICSRYT EIRLVNGKTP CEGRVEIKTL
GTWGSLCNSH WDMEDAHVIC QQLKCGVALS TPGGAHFGKG SGQVWRHMFH CTGTEQHMGD
CPVTVLGASL CSAGQVASVI CSGNQTQILP LCNSSSSDPT SSPIPEESAA GCVGSGQLRL
VNGGGRCAGR VEVYHEGSWG TICDDSWDLS DARVVCRQLG CGVAVNATGS AHFGEGTGPI
WLDELGCNGK ESRIWQCRSH GWGRHNCRHK EDAGVICSEF MSLRLTSETS RQTCAGRLEV
FYNGAWGSVG RSDMSPATVG VVCRQLGCAD RGSISPASSD KTLSRPMWVD HVQCPKGPDT
LWQCPSSPWN QRLASPSEET WITCASKIRL QEGTTNCSGR VEIWHRGSWG TVCDDSWNLE
DAEVVCRQLG CGSALAALKE AEFGQGTGPI WLNEVTCKGT ESSLWDCPAR PWGHSDCGHK
EDAGVRCTGI VETKESPNST GHSFLIALGI LGVILLALLI AFLMWTQKRR QRQRLTVSSR
GENSVHQVQY REMNSCLKAD DLDALNSSGG HYEVH
//
