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Database: UniProt
Entry: A0A2Y9S0B2_TRIMA
LinkDB: A0A2Y9S0B2_TRIMA
Original site: A0A2Y9S0B2_TRIMA 
ID   A0A2Y9S0B2_TRIMA        Unreviewed;      2604 AA.
AC   A0A2Y9S0B2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   10-FEB-2021, entry version 12.
DE   SubName: Full=centromere protein F isoform X1 {ECO:0000313|RefSeq:XP_023597473.1};
GN   Name=LOC101349997 {ECO:0000313|RefSeq:XP_023597473.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023597473.1};
RN   [1] {ECO:0000313|RefSeq:XP_023597473.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (OCT-2020) to UniProtKB.
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DR   RefSeq; XP_023597473.1; XM_023741705.1.
DR   KEGG; tmu:101349997; -.
DR   Proteomes; UP000248480; Genome assembly.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT   DOMAIN          1..306
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1875..1996
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2113..2251
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2295..2434
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   REGION          126..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          207..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          754..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1340..1367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1699..1722
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          279..334
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          349..394
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          417..458
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          462..486
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          508..670
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          678..698
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          703..744
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          824..851
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          884..974
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1014..1094
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1103..1130
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1188..1229
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1279..1313
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1318..1338
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1379..1399
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1556..1594
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1773..1793
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1801..1835
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1872..1906
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1921..1979
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1984..2074
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2089..2116
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2124..2207
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2215..2260
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2278..2298
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2306..2442
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2450..2491
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2499..2519
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2530..2592
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        127..155
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..231
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        754..769
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1699..1719
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2604 AA;  299582 MW;  163384EC0D607BB1 CRC64;
     MSWAVEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LDTLEAALQK QKQKVENEKL
     EGANLKRENQ SLVETCENLE KTRQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ SALPADVSLN PGSTPQKIFP TPLTPSQYYS GSRYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASPGVPQS TMNHREIARH QASSSVFSWQ QEKTPSRLSS SARKTRNRRD
     FPASHLAGEQ DVTPSRSTLQ IGNKDTNSSF CDSSNFHLLD QLKTQNQELR SRISELELQL
     QGQEKELKSQ VNKFQELQLQ METAKVELIE KEKVLNKNSD ELVRTAAQYD QASVQCTALE
     HKLKKLTEDL SCQRQNAEST RYSLEQKMKE REKEFQQELS RQQQCFQTLD RECTQAKAKL
     TQELQQVKNT HSILQAELDK VTSVKQHLEK NLEEFKQKFC RTEQALQEMK KENNLLKSQS
     EQRAREVGHL EEELQKARQC LNQSQKFADE MRVKNTSQET ALRDLQEKIN QQENALTLEK
     LKLALADLEK QRDCSQDLLK KREHHIEQLN EKLSRTEKES QALLSALELK AKEYEELKEE
     KTLLTRWKSE KEQLVNQMEA EKETLQCKIH HLETCLKTQQ VKSQEYNERV QTMEMERENL
     NAEIRNLHNT IDSRSVEIEA QKRAYTELQQ KAELSDQKHK KEIENMCLKA SQLTGQVDEL
     EHKLQLLSNE VREKDQHYRD LHAEYESLRD LLKSKDSSPE MKEDHHTSLL ASEQQPARNN
     SFAKISGEQG SMPLERSECR SAADQSPPDS AVLQNRVISL EFSLESQKQV NSDLQKQCEE
     LVQIKGEIEE NLIRAEQMHH SFVAETNQRI NKLQEDTSVH QNVVAETLVA LENKERELQL
     LSEKLETQQA EYQELKKSNG LLEDSLKELQ LLSETLSSEK KEMNSIISLS KQEIEALTQE
     NRILKEVNAT LNQEKMHLLQ KSESFSSCLD EREKSISELS EQYKQEKLIL LQRCEETGNA
     FESLRENYET VQERNSRLEC LLNECTSLCE NRKKELEQLK ETFAREHQAL LTKLASAEER
     NQSLVLEVGT VQRELRSEIT DIQDNAKGEA DGLRQEISAL KEDQNRRQKE VHALLEENKR
     LMELTKSMPG HQDLELGPIS DSVKERQCEI NKCNAERQME LDVEDTSLDT YNAQLVQLEA
     VVRNMELKLE EREKEKAYLQ QELRRIRGEL ETGNLQQDTQ SQEIAGLKDC EVGAEEKYLS
     VPREMSTSQS DTVRLQCCLQ AVMTKLNELE KTCEILQAEK HQLSSELNDS RLECITATSK
     LAGEVEKLVN EVKILNDENG LHPGELVKPV PEGELGEQQN GSLSPLDDSN VYEHLTLSNK
     EVQTHFAELQ EKFSSLQSEH KILHDQRCQM SSKMSALQSY VDTLKAENSV LSMNLRNFQD
     DLVKEVTLGP EEGSILSLSF SCVTDSPILK SFGESSFCKD LLEQTGEISL LNNLEENISA
     NQPDAAEVSC SSLEEEARAE RGIPSRPVRG TEEPEALCQK CLRSLKKLGG DMESQRIMKN
     KEIQELERLL SSEREELECL RKQHLSENEQ WQQKLTSVTV EMESKLAAEK KQTAHLSLEL
     EVARLQLQGL DLSSRSLLGA GIEDAIRGGN ESCNIKESEE YTPKAKGRTP KHDIRQICED
     VQQDLSLEIE KIAETDAVSQ TGQQFGMPSS DTGSETPLGD EAQGWSECVS ELSFSDPHAL
     VPMDFLETQV TIQNLQVQVK ETSNENLRLL HVIVERERKL ETLLNEVKEL DSEVGLQKVR
     LTTKTEACIE LEKTVEELKE EISDLSEKLR FFSSDNPEVY RKVKTLEDLN SNLETTDKLP
     DEVTEDDVAM VNDSWKEKFL KVENELERIK SENASMEHHI LSMEANLETV QTEKLYLEKD
     NESKQKVITC LEEQLAEVTT ERNQLRGELG TMSRENKELS QMSERMKEKL QQLECHHDEC
     LRHIQVVEAE VKEKRELLQT LSSDANGRLK EKAHLQEQLQ NLQKDSQALS LVKGELENQI
     GQLNKERDLL VRDLESLQNK LSESEEGKAA HSQALEAALV EKGEIAVRLS STQEEVRQLR
     NGIEKLKVRI EADEKKQLHV LEKLKESERH SDALKDKVES LERELQVSEE NQELVILDAE
     NSKAEVETLK EKVEEMAETL KGLELDLVAV RSEKEHLMEQ LREKQSQVLE LEPLLSSLKS
     LIEEKEQEKI QMKEESKTAV ELLQTQLKEL NMEIAALCDD QQPSVAKEES LGSPAEEIRQ
     LRHSIEKLRV RIAEDEKKQL HVLEKLQESE QNADLLKDRV DNLDRELEVA GKNQELVILD
     AENSKAEAET LRIKMEELAQ NLRDLELELA NIKSEKESLT KELQTEQGRV SELEILNSSF
     ENLLQEKEQE KVQMKEESEI AVELLQTQLK ELNEKMAAMC VDQEARTAKE QSLRGQVDSL
     EREKAQLLQS LEEAKNNYIR LQSSVDDLVQ EIEDGRWKLE KKHEEISTLK SQVQDQELLA
     SKLSQVEGER QLWEKQKTEL GNLIMELEQK VQVLQSKNAS LQDILEGLQN SYKDLEKELE
     ATKMEKISFV EKVSGLVYLH LLLF
//
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