UniProt: A0A2Y9S1Q9

Database: UniProt
Entry: A0A2Y9S1Q9_PHYMC

LinkDB:  A0A2Y9S1Q9_PHYMC 
Original site:  A0A2Y9S1Q9_PHYMC

All links

Ontology (5)   
   GO (5)   
Gene (1)   
   KEGG GENES (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
Protein domain (25)   
   InterPro (14)   
   Pfam (7)   
   PROSITE (1)   
   SMART (3)   
All databases (32)   

Download RDF

ID   A0A2Y9S1Q9_PHYMC        Unreviewed;      1919 AA.
AC   A0A2Y9S1Q9;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 2.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Plexin-A3 {ECO:0000313|RefSeq:XP_023972528.2};
GN   Name=PLXNA3 {ECO:0000313|RefSeq:XP_023972528.2};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023972528.2};
RN   [1] {ECO:0000313|RefSeq:XP_023972528.2}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_023972528.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC       Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC   -!- SIMILARITY: Belongs to the plexin family.
CC       {ECO:0000256|ARBA:ARBA00010297}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_023972528.2; XM_024116760.3.
DR   STRING; 9755.ENSPCTP00005019932; -.
DR   KEGG; pcad:102979175; -.
DR   InParanoid; A0A2Y9S1Q9; -.
DR   OrthoDB; 1387371at2759; -.
DR   Proteomes; UP000248484; Chromosome 21.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00603; IPT_PCSR; 1.
DR   CDD; cd01180; IPT_plexin_repeat1; 1.
DR   CDD; cd01179; IPT_plexin_repeat2; 1.
DR   CDD; cd01181; IPT_plexin_repeat3; 1.
DR   CDD; cd12790; RasGAP_plexin_A; 1.
DR   CDD; cd11273; Sema_plexin_A3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR031148; Plexin.
DR   InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR   InterPro; IPR046800; Plexin_RBD.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR041019; TIG1_plexin.
DR   InterPro; IPR041362; TIG2_plexin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR22625; PLEXIN; 1.
DR   PANTHER; PTHR22625:SF32; PLEXIN-A3; 1.
DR   Pfam; PF08337; Plexin_cytopl; 1.
DR   Pfam; PF20170; Plexin_RBD; 1.
DR   Pfam; PF01437; PSI; 3.
DR   Pfam; PF01403; Sema; 1.
DR   Pfam; PF01833; TIG; 4.
DR   Pfam; PF18020; TIG_2; 1.
DR   Pfam; PF17960; TIG_plexin; 1.
DR   SMART; SM00429; IPT; 4.
DR   SMART; SM00423; PSI; 3.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF81296; E set domains; 4.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transferase {ECO:0000256|ARBA:ARBA00022777};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1266..1290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          58..536
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   REGION          20..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1287..1321
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1919 AA;  212051 MW;  9CCA88F55FC07444 CRC64;
     MRPPFSVFLS SLARALRIQD ADLTKEPQRD DQPELKLCSP PPGQPPAMPA VGLLLLFLLA
     VGRAPGGSTP FPAFSVTDTS LTHLAVHRVT GEVFVGAVNR VFKLAPNLTE LRVHVTGPVE
     DNARCYPPPS MRVCAHRLAP VDNVNKLLLI DYAARRLVAC GSIWQGTCQF LRLDDLFKLG
     EPHHRKEHYL SGAQGPDSMA GVIVEQGQGP SKLFVGTAVD GKSEYFPTLS SRKLIGDEDG
     GDMFSLVYQD EFVSSQIKIP SDTLSLYPAF DIYYVYGFVS ASFVYFLTLQ LDTQQTLLDA
     AGEKFFTSKI VRMCSGDSEF YSYVEFPIGC SWRGVEYRLV QSAHLAKPGL LLAQALGVPA
     DEDVLFTIFS QGQKNRASPP RQTILCLFTL SSINAHIRRR IQSCYRGEGT LALPWLLNKE
     LPCINTPMQI NGNFCGLVLN QPLGGLHVIE GLPLLADSTD GMASVAAYTY QQHSVVFIGT
     RSGSLKKVRV DGSQEARLYE TVPVVDGSPI LRDLLFSPDR RHVYLLSEKQ VSQLPVETCE
     QYPSCAACLG SGDPHCGWCV LQHRCCRHGA CAGASAPRGF AKELSKCVQV RVRPNNVSVT
     SPGVQLTVAI SNVPDLSAGV SCAFEEVTES EAVLLPSGEL QCPSPSLQEL RALTRGHGAT
     RTVQLQLLSR ESGVRFAGAD FVFYNCSVLQ SCMSCVGSPY PCHWCKYRHV CTSHPHECSF
     QEGRVHSPEG CPEILPSGDL LIPVGVMQPL TLRAKNLPQP QSGQKNYECV VRAQGRQQRV
     PAVRFNSSSV QCQNASYSYE GDEHGDTELD FSVVWDGDFP IDKPATFRAL LYKCWAQRPS
     CGLCLKADPR FNCGWCISEH RCQLRAHCPA PKTNWMHPNQ KGARCSHPRI AQIHPLVGPK
     EGGTRITIVG ENLGLTSRDV GLRVAGVRCN SIPAEYVSAE RIVCEMEESL VPSPPPGPAE
     LCVSDCSADF RTQSEQLYSF VTPTFDRVSP SRGPASGGTR ITISGHSLDA GSRVTVTVRD
     GECQFVRRDA EAIVCVSPVS TLGPSQAPIT LAIDRANISS PGVLYTYTQD PTVTRLEPTW
     SIVNGSTAIT VSGTHLLTVQ EPRVRAKYRG IETTNTCQVI NDTAMLCKAP GIFLGRPQPQ
     AQGQHPDEFG FLLDHVQTAR SLNRSSFTYY PDPSFEPLGP SGVLDVKPGS HVVLKGKNLI
     PAAAGSSRLN YTVLIGGQPC TLTVSDTQLL CDSPSQTGRQ PVMVLVGGLE FWLGTLHITA
     DRPLTLPAVV GLAAGGGLLL LAIAAVLVAY KRKTQDADRT LKRLQLQMDN LESRVALECK
     EAFAELQTDI NELTNHMDGV QIPFLDYRTY AVRVLFPGIE AHPVLKELDT PPNVEKALRL
     FGQLLHSRAF VLTFIRTLEA QSSFSMRDRG TVASLTMVAL QSRLDYATGL LKQLLADLIE
     KNLESKNHPK LLLRRTESVA EKMLTNWFTF LLHKFLKECA GEPLFLLYCA IKQQMEKGPI
     DAITGEARYS LSEDKLIRQQ IDYKTLTLHC VCPESEGSAQ VPVKVLNCDS ITQAKDKLLD
     AVYKGIPYSQ RPRAEDMDLE WRQGRMARII LQDEDVTTKI ECDWKRVNSL AHYQVTDSSL
     VALVPKQVSA YNMANSFTFT RSLSRYESLL RTASSPDSLR SRAPMITPDQ ETGTKLWHLV
     KNHDHADHRE GDRGSKMVSE IYLTRLLATK GTLQKFVDDL FETVFSTAHR GSALPLAIKY
     MFDFLDEQAD QRQISDPDVR HTWKSNCLPL RFWVNVIKNP QFVFDIHKSS ITDACLSVVA
     QTFMDSCSTS EHRLGKDSPS NKLLYAKDIP NYKSWVERYY RDVAKMASIS DQDMDAYLVE
     QSRLHASDFN VLSALSELYF YVTKYRQEVL TALDRDASCR KQKLRQKLEQ IIGLASSNS
//

DBGET integrated database retrieval system