ID A0A2Y9S307_TRIMA Unreviewed; 677 AA.
AC A0A2Y9S307;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Double-stranded RNA-binding protein Staufen homolog 1 isoform X1 {ECO:0000313|RefSeq:XP_023598808.1, ECO:0000313|RefSeq:XP_023598809.1};
GN Name=LOC101361917 {ECO:0000313|RefSeq:XP_023598808.1,
GN ECO:0000313|RefSeq:XP_023598809.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023598809.1};
RN [1] {ECO:0000313|RefSeq:XP_023598808.1, ECO:0000313|RefSeq:XP_023598809.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_023598808.1; XM_023743040.1.
DR RefSeq; XP_023598809.1; XM_023743041.1.
DR STRING; 127582.A0A2Y9S307; -.
DR KEGG; tmu:101361917; -.
DR OrthoDB; 2882160at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19879; DSRM_STAU1_rpt1; 1.
DR CDD; cd19881; DSRM_STAU1_rpt2; 1.
DR CDD; cd19885; DSRM_STAU1_rpt4; 1.
DR CDD; cd19887; DSRM_STAU1_rpt5; 1.
DR Gene3D; 3.30.160.20; -; 5.
DR Gene3D; 6.10.250.1360; -; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR032478; Staufen_C.
DR PANTHER; PTHR46054:SF2; DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1; 1.
DR PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR Pfam; PF00035; dsrm; 4.
DR Pfam; PF16482; Staufen_C; 1.
DR SMART; SM00358; DSRM; 4.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 4.
DR PROSITE; PS50137; DS_RBD; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 80..147
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 166..256
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 278..351
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 386..454
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 38..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 74480 MW; 9BF24730BD94EA00 CRC64;
MSQVQVQVQN PSAALSGSQI LNKNQSLLSQ PLMSIPSTAS SLPSENAGRP IQNSALPSAS
ITSTSAAAVP SNMAHPKEKT PMCLVNELAR FNKIQPEYKL LREQGPAHCK VFTVQLTLGD
QHWEAEGTSI KKAQHTAAAK ALEGTKFPKP IVRPFRSEGR NPESITPTVE LNALCMKLGK
KPMYKPVDPY SRMQSTYNYN MRGGAYPPRY FYPFPVPPLL YQVELSVGGQ QFNGKGRTRQ
AAKHDAAAKA LRILQNEPLP ERLEVNGRES EEENLNKSEI SQVFEIALKR NLPVNFESFP
LKQVARESGP PHMKSFVTKV SVGQFIGEGE GKSKKISKKN AAIAVLEELK KLPPLPTVER
VKPRIKKKTK SIVKLHTGPE YGQGMNPISR LAQIQQAKKE KEPEYMLLTE RGLPRRREFV
MQVKVGNHTA EGVGTNKKVA KRNAAENMLE ILGFKVPQSQ PAKPALKSEE KTPIKKPGDG
RKVTFFEPGC TDENGTSNKE DEFRMPYLSH QQLPAGILPM VPEVAQAVGV SQGHHTKDLT
RAAPNPAKAT VTAMIARELL YGGTSPTAET ILKNNISSGH VPHGPLTRPS EQLDYLSRVQ
GFQVEYKDFP KNNKNEFVSL INCSSQPPLI SHGIGKDVES CHDMAALNIL KLLSELDQQS
TEMPRTGNGP LSVCGRC
//
