ID A0A2Y9S482_TRIMA Unreviewed; 569 AA.
AC A0A2Y9S482;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=T-cell surface glycoprotein CD5 isoform X1 {ECO:0000313|RefSeq:XP_023598948.1};
GN Name=LOC101359242 {ECO:0000313|RefSeq:XP_023598948.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_023598948.1};
RN [1] {ECO:0000313|RefSeq:XP_023598948.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR RefSeq; XP_023598948.1; XM_023743180.1.
DR AlphaFoldDB; A0A2Y9S482; -.
DR STRING; 127582.A0A2Y9S482; -.
DR KEGG; tmu:101359242; -.
DR InParanoid; A0A2Y9S482; -.
DR OrthoDB; 5322862at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 3.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR InterPro; IPR003566; Tcell_CD5.
DR PANTHER; PTHR47309; T-CELL SURFACE GLYCOPROTEIN CD5; 1.
DR PANTHER; PTHR47309:SF1; T-CELL SURFACE GLYCOPROTEIN CD5; 1.
DR Pfam; PF00530; SRCR; 2.
DR PRINTS; PR00258; SPERACTRCPTR.
DR PRINTS; PR01409; TCELLCD5.
DR SMART; SM00202; SR; 1.
DR SUPFAM; SSF56487; SRCR-like; 3.
DR PROSITE; PS50287; SRCR_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..569
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015969472"
FT TRANSMEM 368..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..132
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 158..261
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 269..361
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT REGION 540..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 106..116
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 569 AA; 62402 MW; 91AD6686E4956ACA CRC64;
MGSQQPPLTT VYLLGVLVTS CLGGFIREDS EIQIRLSNSS SRCQGRLEVR HLDRWLSVCS
ESWGHSRYHE EDATRLAKNL CPQLRCGRAL ELALSLFSST QNKVLCHGSL GSFSNCTSQG
ASPCRTLILI CLEPTTAAPL PTSPPPTTTP EPTAPPRLQL VEGPGGLSCA GVVEFYHGSL
GGTISNGTQN LTQGLGDLIC RHLRCGSFLR HLPEATLKAT PDTRQEWMQW EIQNASCASL
EQCFQKRQPW ERGTAIGLIC SDFQPKVQSR LVGGRGTCEG TVEVRQGGQW AALCDSFPAK
NTARWEEVCQ EQQCGGVNTY RQLDASEKTS LGLICPQKKL SQCHELHKKQ FYCKRVFVTC
QDLRPAGLGA GTVMSIILAL LLLAVLLVVC GPLAYKKLVK KFRQKKQRQW IGPTGMNQNT
TARATQRIEP SSCLPVHLLP PFPAQRPNPS RRLSVAVFSA IRRPSALAYW EYLSIATTRQ
LSGPRSRTAQ PHTWITNTVS PPGIPTSRLI RLLKGPCTVL LPSLITLLTV TTICTGLRGC
KRSGSRDRNS RARPISPENI LHSPLGNDV
//
