ID A0A2Y9S4E5_PHYMC Unreviewed; 442 AA.
AC A0A2Y9S4E5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Sushi repeat-containing protein SRPX isoform X2 {ECO:0000313|RefSeq:XP_023972252.1};
GN Name=SRPX {ECO:0000313|RefSeq:XP_023972252.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023972252.1};
RN [1] {ECO:0000313|RefSeq:XP_023972252.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023972252.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_023972252.1; XM_024116484.3.
DR AlphaFoldDB; A0A2Y9S4E5; -.
DR Ensembl; ENSPCTT00005028315; ENSPCTP00005025718; ENSPCTG00005018362.
DR Proteomes; UP000248484; Chromosome 21.
DR CDD; cd00033; CCP; 3.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 3.
DR InterPro; IPR025232; DUF4174.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR043555; SRPX-like.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR46343; HYR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46343:SF1; SUSHI REPEAT-CONTAINING PROTEIN SRPX; 1.
DR Pfam; PF13778; DUF4174; 1.
DR Pfam; PF02494; HYR; 1.
DR Pfam; PF00084; Sushi; 3.
DR SMART; SM00032; CCP; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR PROSITE; PS50825; HYR; 1.
DR PROSITE; PS50923; SUSHI; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..442
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015846659"
FT DOMAIN 45..95
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 96..154
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 153..237
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 238..297
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 125..152
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 268..295
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 442 AA; 49105 MW; 12CF68E321E23C82 CRC64;
MGSPALRPAL LPLLPLLPLL LRVPPSRGFP DTPWCSPIKV KYGDVYCRAP QGGYYKTALG
TRCDIRCQKG YELHGSSQLI CQSNKRWSDK VICKQKRCPT LAMPANGGFK CVDGAYFNSR
CEYYCSPGYT LKGEQTVTCM DNKAWSGRPA SCVDIEPPRI KCPSVKERIA EPNKLTVRVS
WETPEGRDTA DGILTDVILK GLPPGSHFPE GDHKIQYTVY DRAENKGICK FRVKVRVRRC
GKLNAPENGY MKCSSDGDNY GATCEFSCIG GYELQGSPAR VCQSNLAWSG TEPTCAAMNV
NVGVRTAAAL LDQFYEKRRL FIVSTPTARN LLYRLQLGML QQAQCGLDLR HITVVELVGV
FPTLIGRIGA KIMPPALALQ LRLLLRIPLY TFSMVLVDKH GMDKERYVSL VTPVALFNLI
DTFPLRKEEM VLQAEMGQTC NT
//
