ID A0A2Y9SJC0_PHYMC Unreviewed; 1114 AA.
AC A0A2Y9SJC0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=SR-related and CTD-associated factor 4 isoform X4 {ECO:0000313|RefSeq:XP_023975864.1};
GN Name=SCAF4 {ECO:0000313|RefSeq:XP_023975864.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023975864.1};
RN [1] {ECO:0000313|RefSeq:XP_023975864.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023975864.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_023975864.1; XM_024120096.2.
DR AlphaFoldDB; A0A2Y9SJC0; -.
DR Proteomes; UP000248484; Chromosome 8.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd17005; CID_SFRS15_SCAF4; 1.
DR CDD; cd12461; RRM_SCAF4; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR006569; CID_dom.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034369; SCAF4_RRM.
DR PANTHER; PTHR23140; RNA PROCESSING PROTEIN LD23810P; 1.
DR PANTHER; PTHR23140:SF3; SR-RELATED AND CTD-ASSOCIATED FACTOR 4; 1.
DR Pfam; PF04818; CID; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00582; RPR; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS51391; CID; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 1..139
FT /note="CID"
FT /evidence="ECO:0000259|PROSITE:PS51391"
FT DOMAIN 508..582
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 144..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 853..1114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..393
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..409
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..477
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..895
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..949
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 958..1054
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1114 AA; 122005 MW; EFF004B77D670A9F CRC64;
MDAVNAFNQE LFSLMDMKPP ISRAKMILIT KAAIKAIKLY KHVVQIVEKF IKKCKPEYKV
PGLYVIDSIV RQSRHQFGTD KDVFGPRFSK NITATFQYLY LCPSEDKSKI VRVLNLWQKN
GVFKIEIIQP LLDMAAGTSN AAPVTENVTN NEGSPPPPVK VSSEPSQATT NSIPAVPQLP
SSDAFAAVAQ LFQTTQGQQL QQILQTFQQP PKPQSPAIDN AVMAQVQAIT AQLKTAPTQP
PEQKAAFPQP EQKTAFDKKL LDRFDYDDEP EAVEESKKED AAAAAATAAA TAPAAAAAPP
APAAAVPSVA ATAASPPQAP FGFPGDGMQQ PAYTQHQNMD QFQPRMMAIQ QDPVHHQVPL
PPNGQMPGFG LLPTPPFPPM AQSVIPPTPP VQQPFQTSFQ AQSEPLTQKA HQEMEVEQPC
IQEVKRHLSD NRKSRSRSAS RSPKRRRSRS GSRSRRSRHR RSRSRSRDRR RHSPRSRSQE
RRDREKERER RQKGLPQIKP ETASVCSTTL WVGQLDKRTT QQDVASLLEE FGPIESINMI
PPRGCAYIVM VHRQDAYRAL QKLSRGNYKV NQKSIKIAWA LNKGIKADYK QYWDVELGVT
YIPWDKVKPE ELESFCEGGM LDSDTLNPDW KGIPKKHENE VAQNGGAETS HTEPVSPIPK
PLPVPVPPIP VPAPITVPPP QVPPHQPGPP VVGALQPPTF TPPLGIPPPG FGPGVPPPPP
PPPFLRPGFN PMHLPPGFLP PGPPPPITPP VSIPPPHTPP INIPNLVSGA RGNAESGDSV
KMYGSAVPPA APTNLPTPPV TQPVSLLGTQ GVAPGPVIGL QAPSTGLLGA RPGLIPLQRP
PGMPPPHLPR FPLMPPRPMP PHMMHRGPPP GPGGFGMPPP HGMKGPYPPH GPFVRPGGVP
GLGGPGPGPG GPEDRDGRQP PPQQPPPAPQ PQQQPPTQPP QPPPTQPQPF RNDNRQQFTS
GRDQERFGRR SFGNRVENDR ERYGNRNDDR ENSNRERREW GRRSPERDRH RDLEERNRRS
SGHRDRERDS RDRESRREKE ENRGKEKPEV TDRAGGNKTV EPPISQVGNV DTVSELDKGE
SESAVVKPSE ELPAEATSSV EPEKDSGSAA EAPR
//
