ID A0A2Y9SJS9_PHYMC Unreviewed; 287 AA.
AC A0A2Y9SJS9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Syntaxin-2 isoform X2 {ECO:0000313|RefSeq:XP_023976580.1};
GN Name=STX2 {ECO:0000313|RefSeq:XP_023976580.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023976580.1};
RN [1] {ECO:0000313|RefSeq:XP_023976580.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023976580.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
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DR RefSeq; XP_023976580.1; XM_024120812.3.
DR AlphaFoldDB; A0A2Y9SJS9; -.
DR Proteomes; UP000248484; Chromosome 19.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd15882; SNARE_syntaxin2; 1.
DR CDD; cd00179; SynN; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 1.20.58.70; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR028671; STX2_SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR InterPro; IPR006011; Syntaxin_N.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; SYNTAXIN; 1.
DR PANTHER; PTHR19957:SF36; SYNTAXIN-2; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF00804; Syntaxin; 1.
DR SMART; SM00503; SynN; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 264..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 191..253
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT COILED 36..98
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 287 AA; 33348 MW; 8A7A1044587CD659 CRC64;
MRDRLPDLTA CRKNDDGDTT IVIEKDHFMD EFFHQVEEVR DRIAKIAQYV EEVKKNHSII
LSAPNPEGKI KEELEDLNKE IKETANKIRT KLKSFEQSFD QDESGNRTSV DLRIRRTQHS
VLSRKFVEVM TEYNEAQTLF RERSKGRIQR QLEITGKTTT DDELEEMLES GNPSIFTSDI
ISDSQITRQA LNEIESRHKD IMKLETSIRE LHEMFMDMAT FVETQGEMIN NIEKNVMNAT
DYVEHAKEET KKAIKYQSKA RRKMMFIIIC VVVLLAILGI ILAATLS
//
