ID   A0A2Y9SMH1_PHYMC        Unreviewed;       342 AA.
AC   A0A2Y9SMH1;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2023, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Renalase isoform X1 {ECO:0000313|RefSeq:XP_023976919.2};
GN   Name=RNLS {ECO:0000313|RefSeq:XP_023976919.2};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023976919.2};
RN   [1] {ECO:0000313|RefSeq:XP_023976919.2}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_023976919.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_023976919.2; XM_024121151.2.
DR   STRING; 9755.ENSPCTP00005027744; -.
DR   KEGG; pcad:102986305; -.
DR   InParanoid; A0A2Y9SMH1; -.
DR   OrthoDB; 5394503at2759; -.
DR   Proteomes; UP000248484; Chromosome 20.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   Gene3D; 3.90.660.10; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR040174; RNLS.
DR   PANTHER; PTHR23357:SF1; RENALASE; 1.
DR   PANTHER; PTHR23357; UNCHARACTERIZED; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..342
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5040968031"
FT   DOMAIN          105..303
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   342 AA;  37532 MW;  DD2AACC9C51248AF CRC64;
     MARVLIVGAG LTGSLCAALL RKAAARPLHL AVWDKAGDSG GRMTTASSPH NPQSTVDLGA
     QYITCTPHYA KKHQSFYDEL LAPGVLKPLT SPIEGMVIKE GDCNFVAPHG VSSIINHYLK
     ESGADIYFRQ CVTQINLRND KWEVLRETGS PEQFDIVVLT MPAPQILQLQ GDIVNLISEC
     QRQQLESVSY SSRYALGLFY EAGTKIDVPW AGQYITNNPC IRFISIDNKK RNIESSEIGP
     SLVIHTTVPF GVTYLEHSTE DVRELIFQQL ENILPGLPQP VATKCQKWRH SQVTNAAANS
     PGQMTLHLKP FLVCGGDGFT QSNFDGCITS ALCVLEALKN HI
//