ID A0A2Y9SNN8_PHYMC Unreviewed; 1075 AA.
AC A0A2Y9SNN8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Myocardin-related transcription factor B isoform X1 {ECO:0000313|RefSeq:XP_023979057.1, ECO:0000313|RefSeq:XP_054946844.1};
GN Name=MRTFB {ECO:0000313|RefSeq:XP_023979057.1,
GN ECO:0000313|RefSeq:XP_054946844.1, ECO:0000313|RefSeq:XP_054946845.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023979057.1};
RN [1] {ECO:0000313|RefSeq:XP_023979057.1, ECO:0000313|RefSeq:XP_054946844.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023979057.1,
RC ECO:0000313|RefSeq:XP_054946844.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007108521.1; XM_007108459.1.
DR RefSeq; XP_023979057.1; XM_024123289.3.
DR RefSeq; XP_054946844.1; XM_055090869.1.
DR RefSeq; XP_054946845.1; XM_055090870.1.
DR AlphaFoldDB; A0A2Y9SNN8; -.
DR STRING; 9755.ENSPCTP00005016049; -.
DR Ensembl; ENSPCTT00005017712; ENSPCTP00005016049; ENSPCTG00005011431.
DR InParanoid; A0A2Y9SNN8; -.
DR OrthoDB; 2997330at2759; -.
DR Proteomes; UP000248484; Chromosome 14.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR GO; GO:1902895; P:positive regulation of miRNA transcription; IEA:Ensembl.
DR GO; GO:0045844; P:positive regulation of striated muscle tissue development; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 6.10.140.2040; -; 1.
DR Gene3D; 6.10.150.10; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR043451; Myocardin-like.
DR InterPro; IPR004018; RPEL_repeat.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR22793:SF5; MYOCARDIN-RELATED TRANSCRIPTION FACTOR B; 1.
DR PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR Pfam; PF02755; RPEL; 2.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00707; RPEL; 3.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51073; RPEL; 3.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REPEAT 51..76
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 95..120
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 139..164
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT DOMAIN 400..434
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 560..605
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 184..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..303
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..839
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1075 AA; 116193 MW; 82376A25B05E1BF9 CRC64;
MDHTGALDTE DELGPLAHLA PSPQSEAVAH EFQELSLQSS QHLPPLNERK NVLQLRLQQR
RTREQLVDQG IMPPLKSPAA FHEQIKSLER ARTENFLKHK IRSRPDRSEL VRMHILEETF
AEPSLQATQM KLKRARLADD LNEKIAQRPG PMELVEKNIL PVDSSVKEAI IGVGKEDYPQ
TQGDFSFDED SSDALSPDQP ASQESQGSAA SPSEPKVSES PSPVTTNTPA QFTSVSPAVP
EFLKTPTADQ PPPRSTAPVL PTNTVSSAKP GPALVKQSHP KNPNDKHRSK KCKDPKPRVK
KLKYHQYIPP DQKGEKSEPP MDSNYARLLQ QQQLFLQLQI LSQQQQQHYN YQTILPAPLK
PLNDKNNNSG NPALNNTTSN TPRQNTSAPM RKPGPLPSSL DDLKVSELKT ELKLRGLPVS
GTKLDLIERL KPYQEMNSGG AATSGIVALS TSAIVPSNPE VTMALPVTTL QNSVTSSGST
FKGELPSAGS SNTAHVDSVN SPLPISPAPS EQSSLSAEDA SVADTFTEIM TMMSPSQFLC
SSPLRAASTE DSLSPTSSTL STLELDAAEK DRKLQEKEKQ IEELKRKLEQ EQKLVEVLKM
QLEVEKRGQQ RPLEPPPSTS APPVPKSDQA RGGTAPATKD EALVPDGPSL VAGQTLVAKK
AIVIKQEVPV APAEPPSLVP QFYVSSQGQP PAGVPQPQAL LTTRTAQLLL PVSVPGSGVT
SVQLPVGSLK LQTPPQTGIQ TQPQIATATL SSGLAQTAPQ KQDTFTPHVL SQPQQVRKVF
TNSASNTVLP YQRPPAPAVQ QPFINKTNSS ILQPRSTPLP SLQNGPNPPN KPGSPPPPQQ
FAVQHSLFGS PVPKTKDPPR YEEAIKQTRS AQSSLPEISN AHSQQMDDLF DILIKSGEIS
LPIKEEPSPI SKMRPVTASI TTMPVSTVVS RPPPQVQMAP PISLEPMSSL SASLENQLEA
FLDGTLPSAS EIAPLQSSSE DREPFSLIED LQNDLLSHSG VLDHSHSPME TSEAQFAAST
PCLSLDLSDS NLDNMEWLDI TMPGTSSGLT PLSTTAPSMF SADFLDPQDL PLPWD
//
