ID A0A2Y9STN0_PHYMC Unreviewed; 454 AA.
AC A0A2Y9STN0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Serine incorporator 2 isoform X2 {ECO:0000313|RefSeq:XP_023981533.1};
GN Name=SERINC2 {ECO:0000313|RefSeq:XP_023981533.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023981533.1};
RN [1] {ECO:0000313|RefSeq:XP_023981533.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023981533.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TDE1 family.
CC {ECO:0000256|ARBA:ARBA00006665}.
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DR RefSeq; XP_023981533.1; XM_024125765.3.
DR AlphaFoldDB; A0A2Y9STN0; -.
DR STRING; 9755.ENSPCTP00005023932; -.
DR Ensembl; ENSPCTT00005026403; ENSPCTP00005023972; ENSPCTG00005017054.
DR Proteomes; UP000248484; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005016; TDE1/TMS.
DR PANTHER; PTHR10383; SERINE INCORPORATOR; 1.
DR PANTHER; PTHR10383:SF22; SERINE INCORPORATOR 2; 1.
DR Pfam; PF03348; Serinc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..454
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016144088"
FT TRANSMEM 36..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 454 AA; 50571 MW; 6CE280A01B358A1A CRC64;
MGACLGACSL LSCASCLCGS APCILCSCCP CSHSSTLSRL IFTAFLFLGV LVSVIMLSPS
VESQLYKLPW VCEEVAGSPV VLQGHVDCGS LLGHRAVYRM CFAMAAFFFL FTLLMICVRS
SRDPRAAIQN GFWFFKFLVF VGITVGAFYI PDGSFSNIWF YFGAVGSFVF LLIQLLLLID
FAHSWNQRWL NKAEESGSRA WYAGLFFFTL LFYALSIVAV ALLFIYYTQP GACYEGKVFI
SLNLIFCFCV SIIAILPKVQ DAQPNSGLLQ ASVITLYTMF VTWSALSNVP ERKCNPNLLT
HFGNGTVLAG PEGYETQWWD APSIVGLIIF LLCTLFISLR SSDHRQVNSL MQTEESPPVL
EATQQQQAAG CEGRAFDNEQ DSVTYSYSFF HFCLVLASLH VMMTLTNWYR PGETRKMIST
WTAVWVKICA SWAGLLLYLW TLVAPLLLPN RDFS
//
