ID A0A2Y9SVA7_PHYMC Unreviewed; 672 AA.
AC A0A2Y9SVA7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=G-protein-signaling modulator 1 isoform X2 {ECO:0000313|RefSeq:XP_023982113.1};
GN Name=LOC102983817 {ECO:0000313|RefSeq:XP_023982113.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023982113.1};
RN [1] {ECO:0000313|RefSeq:XP_023982113.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023982113.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR RefSeq; XP_023982113.1; XM_024126345.3.
DR AlphaFoldDB; A0A2Y9SVA7; -.
DR STRING; 9755.ENSPCTP00005014596; -.
DR Ensembl; ENSPCTT00005016092; ENSPCTP00005014546; ENSPCTG00005010276.
DR Ensembl; ENSPCTT00005016176; ENSPCTP00005014617; ENSPCTG00005010276.
DR InParanoid; A0A2Y9SVA7; -.
DR OrthoDB; 4190321at2759; -.
DR Proteomes; UP000248484; Chromosome 13.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954:SF2; G-PROTEIN-SIGNALING MODULATOR 1; 1.
DR PANTHER; PTHR45954; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 4.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 2.
DR SMART; SM00390; GoLoco; 4.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50877; GOLOCO; 4.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 245..278
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 383..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 672 AA; 74050 MW; 0A49143D5AA89715 CRC64;
MAGPAPPAAD ELLGPARRLY SRMEASCLEL ALEGERLCKA GDFKAGVAFF EAAVQVGTED
LKTLSAIYSQ LGNAYFYLKE YARALAYHKH DLLLARTIGD RMGEAKASGN LGNTLKVLGR
FDEAVVCCQR HLDIAQEQGD KVGEARALYN IGNVYHAKGK QLSWNAAQDP GHLPPAVRET
LRRASEFYER NLSLVKELGD RAAQGRACGN LGNTHYLLGS FTEATTFHKE RLAIAKEFGD
KAAERRAYSN LGNAHIFLGR FDVAAEYYKK TLQLSRQLKD QAVEAQACYS LGNTYTLLQD
YERAAEYHLR HLLIAQELAD RVGEGRACWS LGNAYVSMGS PAQALTFAKK HLEISQEIGD
RSGELTARVN VAQLQLALGR LSSPAAAEKP DLAGYEAQGA RPKRTQRLSA ETWDLLRLPL
EREQNGDSHH AGDWRGPGRD SLPLPVRSRK HQEGPDAAER RPREGGHSPL NSADVRVQVP
RTSIPRAPSS DEECFFDLLS KFQSSRMDDQ RCPLEEGQPA AAEATAAPTL EERIAQPSLT
ASPQTEEFFD LIASSQSRRL DDQRASVGSL PGLRITRNNL GHLRGDGDPQ EPGDEFFNML
IKCQSSRIDD QRCPPPDVLP RGPTMPDEDF FSLIQRVQAK RMDEQRVDLA GSPEQEVGGP
PEPRQQCQPG AS
//
