ID A0A2Y9T005_PHYMC Unreviewed; 245 AA.
AC A0A2Y9T005;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Complement C1q subcomponent subunit C {ECO:0000313|RefSeq:XP_023981429.1};
GN Name=C1QC {ECO:0000313|RefSeq:XP_023981429.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023981429.1};
RN [1] {ECO:0000313|RefSeq:XP_023981429.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023981429.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_023981429.1; XM_024125661.3.
DR AlphaFoldDB; A0A2Y9T005; -.
DR STRING; 9755.ENSPCTP00005011838; -.
DR Ensembl; ENSPCTT00005013083; ENSPCTP00005011838; ENSPCTG00005008412.
DR KEGG; pcad:102973652; -.
DR InParanoid; A0A2Y9T005; -.
DR OrthoDB; 3683851at2759; -.
DR Proteomes; UP000248484; Chromosome 3.
DR GO; GO:0062167; C:complement component C1q complex; IEA:Ensembl.
DR GO; GO:0098794; C:postsynapse; IEA:Ensembl.
DR GO; GO:0006958; P:complement activation, classical pathway; IEA:Ensembl.
DR GO; GO:0030853; P:negative regulation of granulocyte differentiation; IEA:Ensembl.
DR GO; GO:0045650; P:negative regulation of macrophage differentiation; IEA:Ensembl.
DR GO; GO:0098883; P:synapse pruning; IEA:Ensembl.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF29; COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..245
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015987158"
FT DOMAIN 115..245
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 44..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 25703 MW; FFF77496DC71F932 CRC64;
MDMGSCSWPP LVPNLLLLFL ALLPGGQAGT DCYGIAGMPG LPGAPGKDGH DGLPGPKGEP
GIPAIPGTRG PKGQKGDPGT PGYPGKNGPM GTPGIPGAPG NMGPPGDPGD EGRYKQNHQS
VFTVTRQTVQ FPAPNSLVKF NSVITNPQRD YDTNTGKFTC KVPGLYYFVY YTSHTANLCV
QLYHSGVKVT TFCDHMSNSK QVSSGSVLLR VQVGEQVWLA VNDYNGMVGT EGSDSVFSGF
LLFPD
//
