ID A0A2Y9T6R1_PHYMC Unreviewed; 485 AA.
AC A0A2Y9T6R1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Septin-6 isoform X4 {ECO:0000313|RefSeq:XP_023983824.1};
GN Name=SEPTIN6 {ECO:0000313|RefSeq:XP_023983824.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023983824.1};
RN [1] {ECO:0000313|RefSeq:XP_023983824.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023983824.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_023983824.1; XM_024128056.3.
DR AlphaFoldDB; A0A2Y9T6R1; -.
DR STRING; 9755.ENSPCTP00005029897; -.
DR Proteomes; UP000248484; Chromosome 21.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF55; SEPTIN-6; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT DOMAIN 90..356
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 372..450
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 453..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 485 AA; 54425 MW; 16756BBECBE17465 CRC64;
MGEVGGGVVE LRDSSGGRSP PSTQRSRSSA VSCAVAPVSA APVAALAEAG AMAATDIARQ
VGEGCRTVPL AGHVGFDSLP DQLVNQSISQ GFCFNILCVG ETGLGKSTLM DTLFNTKFEG
EPATHTQPGV QLRSNTYDLQ ESNVGLKLTI VSTVGFGDQI NKEDSYKPIV EFIDAQFEAY
LQEELKIRRV LHTYHDSRIH ACLYFIAPTG HSLKSLDLVT MKKLDSKVNI IPIIAKSDAI
SKSELTKFKI KITSELVSNG VQIYQFPTDD ELVAEINGTM NAHLPFAVIG STEELKIGNK
MMKARQYPWG TVQVENEAHC DFVKLREMLI RVNMEDLREQ THSRHYELYR RCKLEEMGFK
DTDPDSKPFS LQETYEAKRN EFLGELQKKE EEMRQMFVQR VKEKEAELKE AEKELHEKFD
RLKKLHQDEK KKLEDKKKSL DDEVNAFKQR KTAAELLQSQ GSQAGGSQTL KRDKEKKNNP
WLCTE
//
