ID A0A2Y9TBH2_PHYMC Unreviewed; 876 AA.
AC A0A2Y9TBH2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Zinc finger protein 585A {ECO:0000313|RefSeq:XP_023988250.1};
GN Name=ZNF585A {ECO:0000313|RefSeq:XP_023988250.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023988250.1};
RN [1] {ECO:0000313|RefSeq:XP_023988250.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023988250.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_023988250.1; XM_024132482.3.
DR AlphaFoldDB; A0A2Y9TBH2; -.
DR STRING; 9755.ENSPCTP00005019220; -.
DR KEGG; pcad:102974060; -.
DR InParanoid; A0A2Y9TBH2; -.
DR OrthoDB; 5151920at2759; -.
DR Proteomes; UP000248484; Chromosome 17.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 23.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23234:SF10; GENE 10130-RELATED; 1.
DR PANTHER; PTHR23234; ZNF44 PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 21.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 22.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 14.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 21.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 23.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 29..99
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 237..264
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 265..292
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 293..320
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 321..348
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 349..376
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 377..404
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 405..432
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 433..460
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 461..488
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 489..516
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 517..544
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 545..572
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 573..600
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 601..628
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 629..656
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 657..684
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 685..712
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 713..740
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 741..768
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 769..796
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 797..824
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 825..852
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 853..876
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 876 AA; 100403 MW; CF14A8C453DBBC13 CRC64;
MTMPANWTSH QKSLGLAPEE HGSSCEGSVS FRDVAVDFSR EEWQQLDLDQ KNLYRDVMLE
TYSHLLSVGY QVPETEVFML EQGKEPWTLQ GENPHQSCPE ELWQIDDQIE SYQQRENKSL
RDVAFIKKIL TIKRDYEYKD RKIIHVSQNI PSPKRPHQCD LYGSALSHNL DLHSHNRNSG
SKNINKITEY GKISSCTKHE CTPTGEKLWD HNQCGKILSY KQVPCQHQKS HSGAKSYECV
EFGNIFTRKS QLKVHLKVHT GEKLYVCIDC GKAFVQKPEF ITHQRTHTRE KPYKCSECGK
AFFQVSSLFR HQRIHTGEKL YECSECGKGF SYNSDLSIHQ KIHTGERHHE CSDCGKAFTQ
KSTLKMHQKI HTGERSYICI ECGQAFIQKT HLIAHRRIHT GEKPYECSNC GKSFISKSQL
QVHQRTHTRM KPSICNEYGK VFNNSSNLNT HKKVQMREKS SICTECGKAF TYRSELIIHQ
RIHTGEKPYE CSDCGKAFTQ KSALTVHQRI HTGEKSYICM KCGLAFIQKA HLIAHQIIHT
GEKPYKCGHC GKSFTSKSQL HVHKRIHTGE KPYMCTKCGK AFTNRSNLIT HQKTHTGEKS
YICPKCGKAF TQRSDLITHQ RIHTGEKPYE CNTCGKAFTQ KSHLNIHQKI HTGERQYECH
ECGKAFNQKS ILIVHQKIHT GEKPYVCGEC GRAFIRKSNF ITHQRIHTGE KPYECNDCGK
SFTSKSQLLV HQPIHTGEKP YVCAVCGKAF SGRSNLSKHQ KTHTGEKPYI CSECGKTFRQ
KSELIIHHRI HTGEKPYECS DCGKSFTKKS QLQVHQRIHT GEKPYVCSEC GKAFTDRSNL
NKHQTTHTGD KPYKCVVCGK GFVQKSVLSV HQSIHT
//
