ID A0A2Y9TH05_PHYMC Unreviewed; 249 AA.
AC A0A2Y9TH05;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Interferon-induced transmembrane protein 5 {ECO:0000313|RefSeq:XP_023987539.2};
GN Name=IFITM5 {ECO:0000313|RefSeq:XP_023987539.2};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023987539.2};
RN [1] {ECO:0000313|RefSeq:XP_023987539.2}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_023987539.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CD225/Dispanin family.
CC {ECO:0000256|ARBA:ARBA00006843}.
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DR RefSeq; XP_023987539.2; XM_024131771.3.
DR AlphaFoldDB; A0A2Y9TH05; -.
DR STRING; 9755.ENSPCTP00005023926; -.
DR KEGG; pcad:102994934; -.
DR InParanoid; A0A2Y9TH05; -.
DR OrthoDB; 5322528at2759; -.
DR Proteomes; UP000248484; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007593; CD225/Dispanin_fam.
DR PANTHER; PTHR13999; INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR13999:SF10; INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 5; 1.
DR Pfam; PF04505; CD225; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|RefSeq:XP_023987539.2};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 25956 MW; 9EF110EBF11C6A62 CRC64;
MAPPAALEGA PWAGPPGQEG LWGPRTGPPP LRGQCFSAGG GAFCGGGGLC GGWRGGGWRV
GSRRRGGRGR PLSSGLSFVV KFSGGPVSRA AAGTISGRDA HPRSRSPGEE TALEPMDTSY
PREDPRAPTP SKADGTAHTA LTLGAPRPPP RDHLIWSVFS TLYLNLCCLG FLALAYSIKA
RDQKVTGDLE AARQLGSKAK CYNILATVWA LVPSLLLVVL VTTGALHLSR LAKGSAAFFS
TKFNDSDYD
//
