ID   A0A2Y9TH87_PHYMC        Unreviewed;       961 AA.
AC   A0A2Y9TH87;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=PAX-interacting protein 1 {ECO:0000256|ARBA:ARBA00023858};
DE   AltName: Full=PAX transactivation activation domain-interacting protein {ECO:0000256|ARBA:ARBA00030146};
GN   Name=PAXIP1 {ECO:0000313|RefSeq:XP_023987634.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_023987634.1};
RN   [1] {ECO:0000313|RefSeq:XP_023987634.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_023987634.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_023987634.1; XM_024131866.3.
DR   AlphaFoldDB; A0A2Y9TH87; -.
DR   Proteomes; UP000248484; Chromosome 5.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   CDD; cd17710; BRCT_PAXIP1_rpt2; 1.
DR   CDD; cd17711; BRCT_PAXIP1_rpt3; 1.
DR   CDD; cd17730; BRCT_PAXIP1_rpt4; 1.
DR   CDD; cd17712; BRCT_PAXIP1_rpt5; 1.
DR   CDD; cd18440; BRCT_PAXIP1_rpt6; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 5.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   PANTHER; PTHR23196; PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR23196:SF37; PAX-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF12738; PTCB-BRCT; 2.
DR   Pfam; PF16770; RTT107_BRCT_5; 1.
DR   SMART; SM00292; BRCT; 5.
DR   SUPFAM; SSF52113; BRCT domain; 4.
DR   PROSITE; PS50172; BRCT; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT   DOMAIN          1..86
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          400..493
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          665..746
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          91..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..113
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..146
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..162
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        299..318
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..347
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   961 AA;  107415 MW;  C1CCB0A7030CE744 CRC64;
     MQAEASVVMC WVSPEDRSAL WAMLTFHGGG CQLTLDKKCT HLVVPEPKGE KYECALKRAS
     IKIVTPDWVL DCVAEKTKKD EALYHPRLII YEEEEEEEEE EEEEVENEEQ DSQNEGSTDE
     KSSPASSQGG SPSGDQQFSP KSNTEKSKGE LMFDDSSDSS PEKQERNLNW TPAEVPQLVT
     AKRRLPPGQE PGLINLCANV PPVPGNILPP EVRGNLMASG QNLQSSERSE MIAAWSPAVR
     TLRNITNNAD IQQINRPANV AHILQSLAAP TKTLEPQVNH GQQGHANAAL LSQAKVTPEP
     HLSPPPPPPA PPPVLHLPPQ QALQLQQQPY PPPPHPFRPP PQAHQPQFPP QQQVLQHQLA
     HLQQLQRLHQ QQQMQTQTPQ APPCQLQHQL FGHDPAVEIP EEGFLLGCVF AIADYPEQMS
     DKQLLATWKR IIQAHGGAVD PTFSSRCTHL LCESQVSGLF AQAVKERKRC VTAHWLNAVL
     KKKRLVPPHR ALHFPVAFPP GGRPCSQHII SVTGFVDGDR DDLKLMACLA GARYTGYLCR
     SNTVLICREP TGLKYEKAKE WRIPCVNAQW LGDILLGNLE ALRQIQYGRY TTFSLQDPFA
     PAPHLVSNLL DAWRVPLKVS AELLMGVRLP PKLKQNEAAN VQPSSKRARI EDIPPPTKKL
     TPELTPFVLF TGFEPVQVQQ YIKKLYVLGG EVAESAQKCT HLISSKVTRT VKFLTAISVV
     KHIVTPEWLE ECFKCQKFID EQNYLLRDAE AEVLFSFSLE ESLRRARVSP LFKAKYFYIT
     PGICPSLSTM KAIVECAGGK VLSKQPSFRK LMEHKQNKSL SEIILISCEN DLHLCREYFA
     RGIGMVSSSS CSVFRVCRYT HSSAFLQPFL FSFLSDVHNA EFVLTGVLTQ TLDYESYPLR
     CALRTPAHPR RQLCGPRSSM NEDIFARAGD KRALPFLYLS LGFFLPLGGW WVSPQGPFSC
     I
//