ID A0A2Z2HNG6_9EURY Unreviewed; 495 AA.
AC A0A2Z2HNG6;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=B1756_00955 {ECO:0000313|EMBL:ARS88459.1};
OS Natrarchaeobaculum aegyptiacum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrarchaeobaculum.
OX NCBI_TaxID=745377 {ECO:0000313|EMBL:ARS88459.1, ECO:0000313|Proteomes:UP000250088};
RN [1] {ECO:0000313|Proteomes:UP000250088}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JW/NM-HA 15 {ECO:0000313|Proteomes:UP000250088};
RA Zhao B.;
RT "Natronthermophilus aegyptiacus gen. nov.,sp. nov., an aerobic, extremely
RT halophilic alkalithermophilic archaeon isolated from the athalassohaline
RT Wadi An Natrun, Egypt.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
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DR EMBL; CP019893; ARS88459.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z2HNG6; -.
DR KEGG; naj:B1756_00955; -.
DR Proteomes; UP000250088; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd17926; DEXHc_RE; 1.
DR Gene3D; 3.40.1170.30; -; 1.
DR Gene3D; 6.10.140.1180; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR040699; XPB_DRD.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18458; XPB_DRD; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:ARS88459.1};
KW Helicase {ECO:0000313|EMBL:ARS88459.1};
KW Hydrolase {ECO:0000313|EMBL:ARS88459.1};
KW Nucleotide-binding {ECO:0000313|EMBL:ARS88459.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000250088}.
FT DOMAIN 128..272
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 362..495
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 495 AA; 54500 MW; B28DDF8BC50165AA CRC64;
MSIRSPVSDV TDSSPDAEPI ALRFEEGTVR IDGLEGDIAR EIADGVSDLE ADHRTDGHRV
PAHRYAAVRR GLLESAAVTP TNLDDRVCSL ESVGDLESTY ELRSYQQAAL DAWLETDHWA
ASSASGSQLE LEAAPAGVLE LPTGSGKTVI ALKAIERLAV PTLVVVPTID LLEQWISELE
AEFDCPIGRF GGGEQRLEAI TVSTYDSAYL KADSVGDRFG LVVFDEVHHL GGEGYREIAR
LLAAPARLGL TATFERPDEA HEVIEQLVGP VVHRLAPEDL AGNHLAPYDV KRLEVSLTPE
EREEYDRNQE VFANYLAKSN ISMQSGSDYQ KLVMRSGNDP EARKALLARQ RAREITYGSA
NKLEALESIL DDHRDERTIV FTAHNDLAYE VSERFLIPTI THQTGAGERR EILERFREAT
YTRIATSNVL DEGVDVPDAS VAVVLSGSGS EREFTQRLGR ILRPNDDDSR AILYEVVAAE
TGEERVSSRR RNGGR
//
