ID A0A2Z2HT60_9EURY Unreviewed; 296 AA.
AC A0A2Z2HT60;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:ARS88597.1};
GN ORFNames=B1756_01705 {ECO:0000313|EMBL:ARS88597.1};
OS Natrarchaeobaculum aegyptiacum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrarchaeobaculum.
OX NCBI_TaxID=745377 {ECO:0000313|EMBL:ARS88597.1, ECO:0000313|Proteomes:UP000250088};
RN [1] {ECO:0000313|Proteomes:UP000250088}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JW/NM-HA 15 {ECO:0000313|Proteomes:UP000250088};
RA Zhao B.;
RT "Natronthermophilus aegyptiacus gen. nov.,sp. nov., an aerobic, extremely
RT halophilic alkalithermophilic archaeon isolated from the athalassohaline
RT Wadi An Natrun, Egypt.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP019893; ARS88597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z2HT60; -.
DR KEGG; naj:B1756_01705; -.
DR OrthoDB; 350860at2157; -.
DR Proteomes; UP000250088; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008675; F:2-dehydro-3-deoxy-phosphogluconate aldolase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR InterPro; IPR020625; Schiff_base-form_aldolases_AS.
DR InterPro; IPR020624; Schiff_base-form_aldolases_CS.
DR PANTHER; PTHR42849; N-ACETYLNEURAMINATE LYASE; 1.
DR PANTHER; PTHR42849:SF1; N-ACETYLNEURAMINATE LYASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00665; DHDPS_1; 1.
DR PROSITE; PS00666; DHDPS_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000250088};
KW Schiff base {ECO:0000256|ARBA:ARBA00023270}.
FT ACT_SITE 140
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 168
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 51
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 296 AA; 31036 MW; ADDC0017DD7BBEB3 CRC64;
MTLTDALEGI TTPLVTPFDP ETDAVDERAL ERLVDHLLAN DVDGLFPCGT TGEFASLAPE
ERRLVHEVVV DRADGAIPVL AGAAATSVSE AVAYAEHAAG IGADAAVVTE PYFHGPNDSE
GNRRFLEQVA DQSPLPVLLY NIPPCTGGSL ALETVSALAD HENVVGIKDS SGDLTYMLSI
VRESPDDFLV LQGYDALLVP ALRMGVDGGL NAGSNVAPAT YRELYERADE DHGASIQNAI
APLFDACAEY GFAPATKTAL AHRGVIPSDV VRSPLVPVPD DAHEDIEAGV DALLEG
//
