ID A0A2Z2NQD8_9GAMM Unreviewed; 505 AA.
AC A0A2Z2NQD8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=3-hydroxyadipyl-CoA dehydrogenase {ECO:0000313|EMBL:ASJ73449.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:ASJ73449.1};
GN Name=paaH {ECO:0000313|EMBL:ASJ73449.1};
GN ORFNames=IMCC3135_16835 {ECO:0000313|EMBL:ASJ73449.1};
OS Granulosicoccus antarcticus IMCC3135.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Granulosicoccaceae; Granulosicoccus.
OX NCBI_TaxID=1192854 {ECO:0000313|EMBL:ASJ73449.1, ECO:0000313|Proteomes:UP000250079};
RN [1] {ECO:0000313|EMBL:ASJ73449.1, ECO:0000313|Proteomes:UP000250079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC3135 {ECO:0000313|EMBL:ASJ73449.1,
RC ECO:0000313|Proteomes:UP000250079};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC {ECO:0000256|ARBA:ARBA00005086}.
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DR EMBL; CP018632; ASJ73449.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z2NQD8; -.
DR KEGG; gai:IMCC3135_16835; -.
DR OrthoDB; 5389341at2; -.
DR Proteomes; UP000250079; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ASJ73449.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000250079}.
FT DOMAIN 3..181
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 184..281
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 409..492
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 505 AA; 53891 MW; 78EB3EE32446448B CRC64;
MTTIAVIGTG AMGRGIIQWA AESGATVLAY DQADGAADKA ISFVVGLLDR AVTKNRISQD
VKDDRVSRIK PVSDLSDLAS ADVVIEAILE DLDIKRALFK ELEAVVGRDT LLCTNTSSLS
VTSIAFGCEH PDRVAGLHFF NPVPLMRVVE VISGERTDPK VVQILLDIVK RTQHHPVICS
DNPGFVVNHA GRGLYTEGLR IVQETVAEPV DVDRIIRGSL GLPMGPFELF DLTGLDVSGR
VLHEIYDAFY QEPRYRPAPL VRRRIAAGLL GRKTGAGFYT YVDNKRVEPT EPHASNANAG
SYFIDASGPE AETLATLLIA GGGTLAPAKT AATIIVAPIG RDATTTCIDA GHDPARTLAI
DLLFPTALKQ GGRQTVMTTP ATDSARVDAL VACLSRAGQS ITVIQDSPGF VAQRVAANIV
NTACEIAQMG IATPLDINAG VTGGLGYPLG PLALGDQIGP LRVLEILENL QIATGDPRYR
PSMWLIRRAK LGLSLMHINE KNEKE
//
