ID   A0A2Z2NQY5_9GAMM        Unreviewed;       517 AA.
AC   A0A2Z2NQY5;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase {ECO:0000313|EMBL:ASJ73753.1};
DE            EC=3.6.1.40 {ECO:0000313|EMBL:ASJ73753.1};
GN   Name=gppA {ECO:0000313|EMBL:ASJ73753.1};
GN   ORFNames=IMCC3135_18370 {ECO:0000313|EMBL:ASJ73753.1};
OS   Granulosicoccus antarcticus IMCC3135.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC   Granulosicoccaceae; Granulosicoccus.
OX   NCBI_TaxID=1192854 {ECO:0000313|EMBL:ASJ73753.1, ECO:0000313|Proteomes:UP000250079};
RN   [1] {ECO:0000313|EMBL:ASJ73753.1, ECO:0000313|Proteomes:UP000250079}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMCC3135 {ECO:0000313|EMBL:ASJ73753.1,
RC   ECO:0000313|Proteomes:UP000250079};
RA   Song W.-J., Kurnit D.M.;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP018632; ASJ73753.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2Z2NQY5; -.
DR   KEGG; gai:IMCC3135_18370; -.
DR   OrthoDB; 9793035at2; -.
DR   Proteomes; UP000250079; Chromosome.
DR   GO; GO:0008894; F:guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR048951; Ppx_C.
DR   InterPro; IPR003695; Ppx_GppA_N.
DR   PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR   PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR   Pfam; PF02541; Ppx-GppA; 1.
DR   Pfam; PF21697; Ppx_C; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ASJ73753.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000250079}.
FT   DOMAIN          57..323
FT                   /note="Ppx/GppA phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02541"
FT   DOMAIN          332..507
FT                   /note="Exopolyphosphatase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21697"
SQ   SEQUENCE   517 AA;  56529 MW;  BFB7EA5FEB53A26A CRC64;
     MTAGLSNQTD ADSRIITIDT TRVINRQQSH YGVIDIGSNS IRLVVYDDLS RAPFPRFNEK
     SMVALGAGLD ADGRFTDETI ARALHAIRRL SAIARAMKVE RIDVLATEAT RRAKNGKDLI
     DAIRESTGLE TITLTGEQEA FYSAHGVISG FFKPMGMMGD IGGGSLEVAE VIADRVGERM
     TSMPLGALPV TRKLEEGYSA TKKWIDEILS ESLPPLLTNP VFFAVGGGWR ALARIHIAMN
     NPTIKVVHGY ELPAKDVRAL AISIAKMSPE EVAALPDVPS RRIATLPASA LVMSRVLKKL
     APDRVAFSAY GLREGWLYKQ LDEEEQYRDP LVEAALAIGL PAARVPAFSE ALALWTENLF
     PGETQNDKRL RLAVCALTDI AWREHEKIRA TDSFLRLLQF PFIGLSHPER AFISVAILAR
     YGGKVDDMVK DAVSNLMTSS ELRRAEILGR ALLLGHRFSA SVPEILKQAR LRIDADAVRL
     EILDAGSIPD SDAVQSRLRQ LAKATGLEGA EIVTVSE
//