ID A0A2Z2NVL9_9GAMM Unreviewed; 557 AA.
AC A0A2Z2NVL9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Alcohol dehydrogenase (Acceptor) {ECO:0000313|EMBL:ASJ74081.1};
DE EC=1.1.99.- {ECO:0000313|EMBL:ASJ74081.1};
GN Name=alkJ_5 {ECO:0000313|EMBL:ASJ74081.1};
GN ORFNames=IMCC3135_20015 {ECO:0000313|EMBL:ASJ74081.1};
OS Granulosicoccus antarcticus IMCC3135.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Granulosicoccaceae; Granulosicoccus.
OX NCBI_TaxID=1192854 {ECO:0000313|EMBL:ASJ74081.1, ECO:0000313|Proteomes:UP000250079};
RN [1] {ECO:0000313|EMBL:ASJ74081.1, ECO:0000313|Proteomes:UP000250079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC3135 {ECO:0000313|EMBL:ASJ74081.1,
RC ECO:0000313|Proteomes:UP000250079};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP018632; ASJ74081.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z2NVL9; -.
DR KEGG; gai:IMCC3135_20015; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000250079; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000313|EMBL:ASJ74081.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000250079}.
FT DOMAIN 254..268
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT REGION 533..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 60080 MW; 356FD1C1651C12E6 CRC64;
MKGSYDYIVV GAGSAGAVLA SRLSENPAVN VLLLEAGPKD NSFWIHLPIG YGKTMWSKKY
NWCFHTEPDP GMNNRSIYWP RGKTLGGCSS INGLIYIRGQ REDYDHWAEL GNSGWSYDEL
LPYFIRSERN QRGASEYHGG DGPLSVSDIG DKNELIEAFI SGAGESGVPR TDDFNGEKQE
GAGYYQLTTW KGWRWSTAKG YLKPARNRSN LTVETNAQAT GLILEGKRAV GVRYVQGGIS
HEARATGEVL LSAGALQSPQ LLQLSGIGPA AVLQKFGIPV VHELPGVGEN LQDHLQIRAT
YEATIPTTND QLNSLIGQAK LGLQWLLHRS GPLAVGINQG GCFMKALPDE AKSPDIQFHV
ATLSADMAGG SVHPFSGFTL SVCQLRPESR GHAHIQSADP MVPPAMVPNY LSTDLDRRTA
VASLRAARAI AESASMKPYV KREVKPGPDA TTDEELLEFS RNHGATIFHP SGTCKMGVAS
DPMAVLDERL RVRGIEALRV IDCSSMPTLV SGNTNGPVVA MAEKAVDMIL EDARKGSGSE
DVSARHDPKT EPATTSV
//
